Shou-Wei Ding

TL;DR: This work shows that replication of FHV positive-strand RNA genome produces an approximately 400 bp dsRNA from its 5' terminus that serves as the major Dicer-2 substrate, and provides a model in which small RNA-directed viral immunity is induced during the initiation of viral progeny (+)RNA synthesis and suppressed by B2 inside the viral RNA replication complex.

TL;DR: It is shown that the CMV 2b protein localizes to the nuclei of tobacco suspension cells and whole plants via an arginine‐rich nuclear localization signal, 22KRRRRR27, indicating that PTGS may be blocked in the nucleus.

TL;DR: A comparative view of the antiviral activity of virus-derived small interfering RNAs in fungi, plants, invertebrates and mammals is presented, detailing the mechanisms for their production, amplification and activity.

TL;DR: It is reported that the tomato aspermy cucumovirus 2b protein (Tav2b), when expressed from the unrelated tobacco mosaic tobamovirus (TMV) RNA genome, activates strong host resistance responses to TMV in tobacco which are typical of the gene‐for‐gene disease resistance mechanism.

TL;DR: It is reported that Cmv2b became essential for systemic infections in older N. glutinosa plants or in young seedlings pretreated with salicylic acid (SA), and it is proposed that SA induces virus resistance by potentiating a RNA-silencing antiviral defense that is targeted by Cm v2b.