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Shuanggang Hu
Researcher at Shanghai Jiao Tong University
Publications - 14
Citations - 193
Shuanggang Hu is an academic researcher from Shanghai Jiao Tong University. The author has contributed to research in topics: Endometrium & Gene. The author has an hindex of 3, co-authored 14 publications receiving 128 citations. Previous affiliations of Shuanggang Hu include Laboratory of Molecular Biology.
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Journal ArticleDOI
Transcriptomic changes during the pre-receptive to receptive transition in human endometrium detected by RNA-Seq.
Shuanggang Hu,Guangxin Yao,Yang Wang,Haijing Xu,Xiaowei Ji,Yaqiong He,Qinling Zhu,Zi-Jiang Chen,Yun Sun +8 more
TL;DR: This study provides the first RNA-Seq-based transcriptome comparison of pre-receptive and receptive human endometria, and identifies many novel candidate genes that may have functional significance during implantation and serve as molecular markers for endometrial receptivity.
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Emerging roles for PIWI proteins in cancer.
TL;DR: PIWI proteins are linked to the hallmarks of cancer defined by Weinberg and Hanahan, such as cell proliferation, anti-apoptosis, genomic instability, invasion and metastasis, which provides new possibilities for anticancer therapies through the targeting of PIWI proteins.
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A Novel Molecule in Human Cyclic Endometrium: LncRNA TUNAR Is Involved in Embryo Implantation
Yuan Wang,Shuanggang Hu,Guangxin Yao,Qinling Zhu,Yaqiong He,Yao Lu,Jia Qi,Rui Xu,Ying Ding,Jiaxing Li,Xinyu Li,Yun Sun +11 more
TL;DR: TUNAR was found expressed in human endometrium for the first time, which might be involved in embryo implantation by modulating the blastocyst attachment to the endometrial epithelium and regulating the proliferation and decidualization of ESCs.
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The dynamic metabolomic changes throughout mouse epididymal lumen fluid potentially contribute to sperm maturation
Shuanggang Hu,Shuanggang Hu,A.-J. Liang,Guangxin Yao,Guangxin Yao,X.-Q. Li,M. Zou,J.-W. Liu,Yu Sun +8 more
TL;DR: The metabolic profiles of mouse caput and cauda epididymal lumen fluids are identified and compared using GC‐MS technique and ascorbate, dehydroascorbic acid and beta‐alanine associated with these two pathways might play important roles in sperm maturation.
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Addressing the role of 11β-hydroxysteroid dehydrogenase type 1 in the development of polycystic ovary syndrome and the putative therapeutic effects of its selective inhibition in a preclinical model.
Xinyu Li,Shuanggang Hu,Qinling Zhu,Guangxin Yao,Jufang Yao,Jiaxing Li,Yuan Wang,Ying Ding,Jia Qi,Rui Xu,Hanting Zhao,Zhenyi Zhu,Yanzhi Du,Kang Sun,Yun Sun +14 more
TL;DR: In this paper, the authors explored the role of 11β-hydroxysteroid dehydrogenases-1 (11β-HSD1) in polycystic ovarian syndrome (PCOS) development.