S
Shuanping Shi
Researcher at Rockefeller University
Publications - 1
Citations - 952
Shuanping Shi is an academic researcher from Rockefeller University. The author has contributed to research in topics: Gene silencing & RNA interference. The author has an hindex of 1, co-authored 1 publications receiving 882 citations.
Papers
More filters
Journal ArticleDOI
Mechanisms and optimization of in vivo delivery of lipophilic siRNAs
Christian Wolfrum,Shuanping Shi,K. Narayanannair Jayaprakash,Muthusamy Jayaraman,Gang Wang,Rajendra K. Pandey,Kallanthottathil G. Rajeev,Tomoko Nakayama,Klaus Charrise,Esther Ndungo,Tracy Zimmermann,Victor Koteliansky,Muthiah Manoharan,Markus Stoffel,Markus Stoffel,Markus Stoffel +15 more
TL;DR: It is shown that conjugation to bile acids and long-chain fatty acids, in addition to cholesterol, mediates siRNA uptake into cells and gene silencing in vivo and can be exploited to optimize therapeutic siRNA delivery.