Shuhui Yang

TL;DR: The present study provides a promising approach for in vivo cartilage repair without cell transplantation and demonstrates that the composite scaffold could enhance endogenous stem cell homing and chondrogenic differentiation and significantly improve the therapeutic outcome of chondral defects.

TL;DR: A biodegradable and self-electrified conduit device is achieved to offer postoperative electrical cues for nerve regeneration, which can provide sustained electrical stimuli beyond intraoperative window and can promote calcium activity, repopulation of Schwann cells, and neurotrophic factors.

TL;DR: Findings indicate that the DCM-RAD/SKP can recruit endogenous stem cells into the site of cartilage injury and promote differentiation of the infiltrating cells intoThe chondrogenic lineage, holding great potential as a one-step surgery strategy for cartilage repair.

TL;DR: The functionalized peptide hydrogel significantly improved the number of newly formed blood vessels, the density of regenerating axons, the morphometric analysis of the regenerated muscles and the electrophysiological findings, indicating the synergistic effect of the two bioactive motifs on peripheral nerve regeneration.

TL;DR: The bioactive peptide motifs were covalently linked to the C-terminal of the self-assembling peptide and the functionalized peptides could form well-defined nanofibrous hydrogels capable of providing a 3D microenvironment similar to native extracellular matrix.