Sidney Behringer

TL;DR: The usefulness and limitations of current biomarkers of B 12 status in newborn screening, infant and adult diagnostics, the algorithms utilized to diagnose B12 deficiency and unusual findings of vitamin B12 status in various human disorders are discussed.

TL;DR: Plasma holo-TC may be a fast-responding biomarker to monitor adequate supply of vitamin B12 in plant-based individuals to reduce the risk of micronutrient deficiencies in Vegans.

TL;DR: The hepatic effects of long‐term supplementation with MCT or triheptanoin, an odd‐chain C7‐based triglyceride, in wild‐type and VLCAD‐deficient mice after 1 year of supplementation as compared with a control diet are explored, raising the question of whether long-term MCFA supplementation represents the most efficient treatment in the long term.

TL;DR: The outcome of enzyme testing in lymphocytes as a confirmatory tool in newborns identified by screening, and the correlation with molecular sequencing of the ACADVL gene are demonstrated.

TL;DR: Analysis of fibroblasts, endothelial and epithelial cells, human embryonic stem cells, and cancer cell lines showed cell specificity for both the speciation and concentration of thiol and thioether metabolites.