Sigbert Jahn

TL;DR: DP IV, an ectoenzyme in the cell membrane of T lymphocytes, is an important constituent in the process of lymphocyte activation and as a consequence of impaired T cell function the production of immunoglobulins by pokeweed mitogen‐stimulated lymphocytes is also markedly reduced in the presence of DP IV inhibitors.

TL;DR: The construction of a new heteromyeloma cell line derived from xenogeneic somatic cell hybridization between normal human B lymphocytes and the murine HAT-sensitive P3X63Ag8/653 cell line and the generation of hybrids secreting human monoclonal antibodies to human immunodeficiency virus is described.

TL;DR: Interestingly, a stage-dependent decrease in T-cell activation antigen expression was observed, suggesting the development of a lack in tumor surveillance in advanced MF stages.

TL;DR: Analysis of the nucleotide sequence level of V H -D-J H transcripts provides evidence that an antigen-triggered clonal B cell expansion takes place in the salivary glands of patients with SS who do not have histologic evidence of developing lymphoma.

TL;DR: The data indicate a germinal center cell origin of primary cutaneous follicle center cell lymphomas and large B cell lymphoma independent of those belonging to one of these subentities.