S
Sih Min Tan
Researcher at Monash University
Publications - 34
Citations - 1290
Sih Min Tan is an academic researcher from Monash University. The author has contributed to research in topics: Diabetes mellitus & Diabetic nephropathy. The author has an hindex of 17, co-authored 31 publications receiving 951 citations. Previous affiliations of Sih Min Tan include Baker IDI Heart and Diabetes Institute & Monash University, Clayton campus.
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Journal ArticleDOI
Dietary advanced glycation end products and risk factors for chronic disease: a systematic review of randomised controlled trials
TL;DR: The evidence presented indicates that a high AGE diet may contribute to risk factors associated with chronic disease, such as inflammation and oxidative stress, however, due to a lack of high quality randomised trials, more research is required.
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Targeted inhibition of activin receptor-like kinase 5 signaling attenuates cardiac dysfunction following myocardial infarction.
Sih Min Tan,Yuan Zhang,Kim A. Connelly,Kim A. Connelly,Richard E. Gilbert,Richard E. Gilbert,Darren J. Kelly +6 more
TL;DR: Treatment with a novel TGF-beta type I receptor inhibitor, GW788388, significantly reduced TGF -beta activity, leading to the attenuation of systolic dysfunction and left ventricular remodeling in an experimental rat model of MI.
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Expression, Localization, and Function of the Thioredoxin System in Diabetic Nephropathy
Andrew Advani,Richard E. Gilbert,Kerri Thai,Renae M. Gow,Robyn G Langham,Alison J. Cox,Kim A. Connelly,Yuan Zhang,Andrew M. Herzenberg,Per K. Christensen,Carol A. Pollock,Weier Qi,Sih Min Tan,Hans-Henrik Parving,Darren J. Kelly +14 more
TL;DR: Findings suggest that impaired thiol reductive capacity contributes to the generation of reactive oxygen species in diabetes in a site- and cell-specific manner.
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Derivative of bardoxolone methyl, dh404, in an inverse dose-dependent manner lessens diabetes-associated atherosclerosis and improves diabetic kidney disease.
Sih Min Tan,Arpeeta Sharma,Nada Stefanovic,Derek Y.C. Yuen,Tom C. Karagiannis,Colin J. Meyer,Keith W. Ward,Mark E. Cooper,Judy B. de Haan +8 more
TL;DR: It is shown that dh404, at lower but not higher doses, significantly lessens diabetes-associated atherosclerosis with reductions in oxidative stress and proinflammatory mediators tumor necrosis factor-α, intracellular adhesion molecule-1, vascular cell adhesion molecules- 1, and monocyte chemotactic protein-1 (MCP-1).
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Mapping time-course mitochondrial adaptations in the kidney in experimental diabetes.
Melinda T. Coughlan,Melinda T. Coughlan,Tuong-Vi Nguyen,Sally A. Penfold,Gavin C Higgins,Gavin C Higgins,Vicki Thallas-Bonke,Sih Min Tan,Sih Min Tan,Nicole J Van Bergen,Karly C. Sourris,Karly C. Sourris,Brooke E. Harcourt,David R. Thorburn,Ian A. Trounce,Mark E. Cooper,Mark E. Cooper,Josephine M. Forbes,Josephine M. Forbes +18 more
TL;DR: Data show that changes in mitochondrial bioenergetics and dynamics may precede the development of the renal lesion in diabetes, and this supports the hypothesis that mitochondrial dysfunction is a primary cause of DKD.