Silvia Santopolo

TL;DR: The present data prove that DAG2 is a positive regulator of the light-mediated seed germination process, and particularly reveal that this protein plays its main role downstream of PIL5 and DAG1 in the phytochrome B (phyB)-mediated pathway.

TL;DR: This work has demonstrated that DAG1 specifi­ cally represses AtGA3ox1 expression, and confirmed that GAI plays a role in the regulation of GA metabolic genes, and in particular of AtGA2ox1, and performed a quantitative RT–PCR analysis on gai-t6 mutant seeds.

TL;DR: It is shown that RGA and GAI play distinct roles in seed germination, and that GAI interacts with DAG1 in embryo development.

TL;DR: In this article , the authors demonstrate that nitazoxanide, an antiprotozoal agent with recognized broad-spectrum antiviral activity, interferes with SARS-CoV-2 spike maturation, hampering its terminal glycosylation at an endoglycosidase H-sensitive stage.

TL;DR: The results indicate that nitazoxanide, due to its broad-spectrum anti-coronavirus activity, may represent a readily available useful tool in the treatment of seasonal coronavirus infections.