Simon V. Hunt

TL;DR: It is shown that monoclonal antibodies against rat and human transferrin receptors label blood capillaries in the brain but not in other tissues, suggesting that transferrin receptor expression on neuronal and glial cells may allow transport of transferrin into brain tissues.

TL;DR: It is shown that small lymphocytes from the thoracic duct of rats are normally a mixture of thymus-derived and marrow-derived cells, and define the traffic areas in lymphoid tissues through which the two populations recirculate, andificially reconstituted mixtures of marrow- derived and thymUS-derived lymphocytes were qualitatively indistinguishable from normal lymphocyte populations.

TL;DR: A mouse monoclonal IgG2a antibody, designated MRC OX-26, is shown to be specific for the rat transferrin receptor, but does not block transferrin binding.

TL;DR: Findings undermine the widely held belief of a categorical divide between excitable and non-excitable tissue calcium channels, demonstrate the limitations of the capacitative calcium influx theory, and point to a distinction between the calcium response mechanisms utilized by B and T lymphocytes.

TL;DR: It is demonstrated that the L-type "voltage-dependent" Ca(2+) channel Ca(V)1.4 plays a cell-intrinsic role in the function, development, and survival of naive T cells and functions in controlling naive T-cell homeostasis and antigen-driven T cell immune responses.