S
Simona Baldi
Researcher at University of Pisa
Publications - 77
Citations - 5970
Simona Baldi is an academic researcher from University of Pisa. The author has contributed to research in topics: Insulin & Insulin resistance. The author has an hindex of 34, co-authored 71 publications receiving 5275 citations.
Papers
More filters
Journal ArticleDOI
Metabolic response to sodium-glucose cotransporter 2 inhibition in type 2 diabetic patients
Ele Ferrannini,Elza Muscelli,Silvia Frascerra,Simona Baldi,Andrea Mari,Tim Heise,Uli C. Broedl,Hans-Juergen Woerle +7 more
TL;DR: In patients with type 2 diabetes, empagliflozin-induced glycosuria improved β cell function and insulin sensitivity, despite the fall in insulin secretion and tissue glucose disposal and the rise in EGP after one dose, thereby lowering fasting and postprandial glycemia.
Journal ArticleDOI
Insulin resistance in non-diabetic patients with non-alcoholic fatty liver disease: sites and mechanisms
Elisabetta Bugianesi,Amalia Gastaldelli,Ester Vanni,Roberto Gambino,Maurizio Cassader,Simona Baldi,V. Ponti,Gianfranco Pagano,Eleuterio Ferrannini,Mario Rizzetto +9 more
TL;DR: Insulin resistance appears to be an intrinsic defect in NAFLD, with the metabolic pattern observed indicating that adipose tissue is an important site and lipid oxidation was significantly related to endogenous glucose production, glucose disposal, the degree of hepatic steatosis, and LDL oxidisability.
Journal ArticleDOI
Shift to Fatty Substrate Utilization in Response to Sodium-Glucose Cotransporter 2 Inhibition in Subjects Without Diabetes and Patients With Type 2 Diabetes.
Ele Ferrannini,Simona Baldi,Silvia Frascerra,Brenno Astiarraga,Tim Heise,Roberto Bizzotto,Andrea Mari,Thomas R. Pieber,Elza Muscelli +8 more
TL;DR: It is concluded that by shunting substantial amounts of carbohydrate into urine, SGLT2-mediated glycosuria results in a progressive shift in fuel utilization toward fatty substrates.
Journal ArticleDOI
Effect of insulin on uric acid excretion in humans
A. Quinones Galvan,Andrea Natali,Simona Baldi,Silvia Frascerra,G Sanna,Demetrio Ciociaro,Ele Ferrannini +6 more
TL;DR: Physiological hyperinsulinemia acutely reduces urinary UA and Na excretion in a coupled fashion and was associated with a 30% fall in urine Na excrete.
Journal ArticleDOI
Liver enzymes, the metabolic syndrome, and incident diabetes: the Mexico City diabetes study.
Monica Nannipieri,Clicerio Gonzales,Simona Baldi,Rosalinda Posadas,Kenneth C. Williams,Steven M. Haffner,Michael P. Stern,Ele Ferrannini +7 more
TL;DR: Although mild elevations in liver enzymes are associated with features of the metabolic syndrome, only raised GGT is an independent predictor of deterioration of glucose tolerance to IGT or diabetes.