R
Roberto Gambino
Researcher at University of Turin
Publications - 175
Citations - 15129
Roberto Gambino is an academic researcher from University of Turin. The author has contributed to research in topics: Insulin resistance & Nonalcoholic fatty liver disease. The author has an hindex of 54, co-authored 173 publications receiving 13103 citations.
Papers
More filters
Journal ArticleDOI
Meta-analysis: Natural history of non-alcoholic fatty liver disease (NAFLD) and diagnostic accuracy of non-invasive tests for liver disease severity
TL;DR: NAFLD warrants screening for cardio-metabolic risk and for progressive liver disease and the combination of three noninvasive tests with LB may optimally individuate patients with NASH, with or without advanced fibrosis.
Journal ArticleDOI
Nonalcoholic steatohepatitis, insulin resistance, and metabolic syndrome: Further evidence for an etiologic association
Gianfranco Pagano,Giovanni Pacini,Giovanni Musso,Roberto Gambino,Fabio Mecca,Nadia Depetris,Maurizio Cassader,Ezio David,Paolo Cavallo-Perin,Mario Rizzetto +9 more
TL;DR: Hyperinsulinemia and insulin resistance occur frequently in patients with NASH; these conditions do not stem from a reduced hepatic insulin extraction but from an enhanced pancreatic insulin secretion compensatory to reduced insulin sensitivity.
Journal ArticleDOI
Dietary habits and their relations to insulin resistance and postprandial lipemia in nonalcoholic steatohepatitis
Giovanni Musso,Roberto Gambino,Franco De Michieli,Maurizio Cassader,Mario Rizzetto,Marilena Durazzo,Emanuela Fagà,Barbara Silli,Gianfranco Pagano +8 more
TL;DR: Dietary habits may promote steatohepatitis directly by modulating hepatic triglyceride accumulation and antioxidant activity as well as indirectly by affecting insulin sensitivity and postprandial triglyceride metabolism.
Journal ArticleDOI
Insulin resistance in non-diabetic patients with non-alcoholic fatty liver disease: sites and mechanisms
Elisabetta Bugianesi,Amalia Gastaldelli,Ester Vanni,Roberto Gambino,Maurizio Cassader,Simona Baldi,V. Ponti,Gianfranco Pagano,Eleuterio Ferrannini,Mario Rizzetto +9 more
TL;DR: Insulin resistance appears to be an intrinsic defect in NAFLD, with the metabolic pattern observed indicating that adipose tissue is an important site and lipid oxidation was significantly related to endogenous glucose production, glucose disposal, the degree of hepatic steatosis, and LDL oxidisability.
Journal ArticleDOI
Recent insights into hepatic lipid metabolism in non-alcoholic fatty liver disease (NAFLD).
TL;DR: This work will review available data on different steps of hepatic lipid metabolism in NAFLD and recent advances in understanding molecular mechanisms underlying hepatic fat accumulation in these subjects.