S
Sixue Zhang
Researcher at Southern Research Institute
Publications - 1
Citations - 77
Sixue Zhang is an academic researcher from Southern Research Institute. The author has contributed to research in topics: GSK-3 & Proteotoxicity. The author has an hindex of 1, co-authored 1 publications receiving 38 citations.
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β-amyloid redirects norepinephrine signaling to activate the pathogenic GSK3β/tau cascade
Fang Zhang,Mary C. Gannon,Yunjia Chen,Shun Yan,Sixue Zhang,Wendy Feng,Jiahui Tao,Bingdong Sha,Zhenghui Liu,Takashi Saito,Takaomi C. Saido,C. Dirk Keene,Kai Jiao,Erik D. Roberson,Huaxi Xu,Qin Wang +15 more
TL;DR: A previously unappreciated direct role of norepinephrine signaling is revealed in connecting β-amyloid and tau, two key pathological components of AD pathogenesis, which provides translational insights into mechanisms underlying Aβ proteotoxicity.