S
Smriti Shukla
Researcher at Indian Institute of Toxicology Research
Publications - 14
Citations - 391
Smriti Shukla is an academic researcher from Indian Institute of Toxicology Research. The author has contributed to research in topics: Oxidative stress & Glutathione. The author has an hindex of 8, co-authored 13 publications receiving 336 citations. Previous affiliations of Smriti Shukla include Council of Scientific and Industrial Research.
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Biochemical and molecular mechanisms of N-acetyl cysteine and silymarin-mediated protection against maneb- and paraquat-induced hepatotoxicity in rats
Israr Ahmad,Smriti Shukla,Ashutosh Kumar,Brajesh K. Singh,Vinod Kumar,Amit Kumar Singh Chauhan,Dhirendra Singh,Haushila Prasad Pandey,Chetna Singh +8 more
TL;DR: It is suggested that NAC and SIL protect MB and/or PQ-induced hepatotoxicity by reducing oxidative stress, inflammation and by modulating xenobitic metabolizing machinery and SIL seems to be more effective.
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The involvement of nitric oxide in maneb- and paraquat-induced oxidative stress in rat polymorphonuclear leukocytes.
TL;DR: The results suggest that MB and/or PQ induce iNOS-mediated nitric oxide production, which in turn increases MPO activity and lipid peroxidation, thereby oxidative stress.
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Effect of zinc and paraquat co-exposure on neurodegeneration: Modulation of oxidative stress and expression of metallothioneins, toxicant responsive and transporter genes in rats.
Ashutosh Kumar,Israr Ahmad,Smriti Shukla,Brajesh K. Singh,Devendra Kumar Patel,Haushila Prasad Pandey,Chetna Singh +6 more
TL;DR: The results obtained suggest that, similar to PQ, Zn induced neurodegeneration via alterations in oxidative stress and expression of the above-mentioned genes, however, the effect of Zn+PQ was only slightly higher than that of alone, indicating that probably Zn and PQ follow some different molecular events leading to neurodegenersation.
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Involvement of NADPH oxidase and glutathione in zinc-induced dopaminergic neurodegeneration in rats: Similarity with paraquat neurotoxicity
Ashutosh Kumar,Brajesh Kumar Singh,Israr Ahmad,Smriti Shukla,Devendra Kumar Patel,Garima Srivastava,Vinod Kumar,Haushila Prasad Pandey,Chetna Singh +8 more
TL;DR: It is suggested that Zn induces oxidative stress via the activation of NADPH oxidase and depletion of GSH, which in turn activate the apoptotic machinery leading to dopaminergic neurodegeneration similar to PQ.
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Certain integrals for classes of p -valent meromorphic functions
Vinod Kumar,Smriti Shukla +1 more
TL;DR: In this article, the authors introduced two classes of functions regular and p-valent in D − {0} where D = {z : |z| < 1} and showed that, for suitable choices of real constants α, β and γ, the integral operators of the form map into, where is the class of pvalent meromorphically starlike functions of order ρ, 0 ≤ ρ < 1.