So-Young Lee

TL;DR: It is now clear that the innate immune system is very important for self or non-self recognition in vertebrates and that it provides instruction that enable the adaptive immune response to enhance immunogenicity.

TL;DR: An antibacterial peptide with 16 amino acid residues was found in plasma of the freshwater crayfish, Pacifastacus leniusculus, and it was purified by cation-exchange column chromatography and reverse-phase high performance liquid chromatography, suggesting that the amino-terminal part of astacidin 1 contributes to the antibacterial activity.

TL;DR: This study shows that differentiation and growth of hemopoietic stem cells in vitro from an invertebrate, Pacifastacus leniusculus, require an endogenous cytokine-like factor, astakine, containing a prokineticin (PK) domain.

TL;DR: The recombinant clip-domain in crayfish proppA was overexpressed in Escherichia coli and the resulting peptide exhibited antibacterial activity against Gram-positive bacterial strains such as Micrococcus luteus Ml11 and Bacillus megaterium Bm11 with 50% growth inhibitory concentrations.

TL;DR: PN-AMPs are the first hevein-like proteins that show similar fungicidal effects as thionins do and exhibited potent antifungal activity against both chitin-containing and non-chitin -containing fungi in the cell wall.