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Sohan Deshpande

Researcher at York University

Publications -  29
Citations -  3256

Sohan Deshpande is an academic researcher from York University. The author has contributed to research in topics: Systematic review & Cost effectiveness. The author has an hindex of 16, co-authored 26 publications receiving 2616 citations.

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Lenalidomide for the Treatment of Low- or Intermediate-1-Risk Myelodysplastic Syndromes Associated with Deletion 5q Cytogenetic Abnormality: An Evidence Review of the NICE Submission from Celgene.

TL;DR: The National Institute for Health and Care Excellence (NICE) invited the manufacturer of lenalidomide (Celgene) to submit evidence of the clinical and cost effectiveness of the drug for treating adults with myelodysplastic syndromes associated with deletion 5q cytogenetic abnormality, and the NICE’s subsequent decisions are described.
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Clinically inappropriate post hoc exclusion of study participants from test accuracy calculations: the ROMA score, an example from a recent NICE diagnostic assessment.

TL;DR: The results illustrate the potential consequences of inappropriate population selection in diagnostic studies; women with non-epithelial ovarian cancers or non-ovarian primaries, and those borderline tumours may be disproportionately represented among those with false negative, ‘low risk’ ROMA scores.
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Predictors of Erythropoiesis-Stimulating Agent Failure in Lower-Risk Myelodysplastic Syndromes: Systematic Literature Review

TL;DR: A systematic literature review (SLR) was conducted to assess quantitative associations between prognostic factors and response to treatment with erythropoiesis-stimulating agents (ESAs) in patients with lower-risk myelodysplastic syndromes as discussed by the authors .