S
Sohyoung Kim
Researcher at National Institutes of Health
Publications - 20
Citations - 565
Sohyoung Kim is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Chromatin & Glucocorticoid receptor. The author has an hindex of 10, co-authored 20 publications receiving 500 citations. Previous affiliations of Sohyoung Kim include George Mason University.
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Journal Article
Diagnostic Markers That Distinguish Colon and Ovarian Adenocarcinomas Identification by Genomic, Proteomic, and Tissue Array Profiling
Satoshi Nishizuka,Sing Tsung Chen,Fuad G. Gwadry,Jes Alexander,Jes Alexander,Sylvia M. Major,Uwe Scherf,William C. Reinhold,Mark Waltham,Mark Waltham,Lu Charboneau,Lynn Young,Kimberly J. Bussey,Sohyoung Kim,Samir Lababidi,Jae K. Lee,Jae K. Lee,Stefania Pittaluga,Dominic A. Scudiero,Edward A. Sausville,Peter J. Munson,Emmanuel F. Petricoin,Lance A. Liotta,Stephen M. Hewitt,Mark Raffeld,John N. Weinstein +25 more
TL;DR: A multistep process starting with the 60 human cancer cell lines used by the National Cancer Institute to screen for new anticancer agents has the potential to produce additional markers for cancer diagnosis, prognosis, and therapy.
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Depicting combinatorial complexity with the molecular interaction map notation
TL;DR: This work focuses on signaling from the epidermal growth factor receptor family (EGFR, ErbB), a network that reflects the major challenges of representing in a compact manner the combinatorial complexity of multimolecular complexes.
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Detailed DNA methylation profiles of the E-cadherin promoter in the NCI-60 cancer cells
William C. Reinhold,Mark Reimers,Alika K. Maunakea,Sohyoung Kim,Samir Lababidi,Uwe Scherf,Uma Shankavaram,Micah S. Ziegler,Claudia Stewart,Hosein Kouros-Mehr,Hengmi Cui,Douglas Dolginow,Dominic A. Scudiero,Yves Pommier,David J. Munroe,Andrew P. Feinberg,John N. Weinstein +16 more
TL;DR: This study provides a type of detailed analysis of methylation that can also be applied to other cancer-related genes, and found E-cad expression to be correlated with E- cad methylation at highly statistically significant levels.
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Targeted H3R26 deimination specifically facilitates estrogen receptor binding by modifying nucleosome structure.
Michael J. Guertin,Xuesen Zhang,Lynne J. Anguish,Sohyoung Kim,Lyuba Varticovski,John T. Lis,Gordon L. Hager,Scott A. Coonrod +7 more
TL;DR: The genomic distributions of ER and H3R26Cit in breast cancer cells are strikingly coincident, linearly correlated, and observed as early as 2 minutes following estradiol treatment.
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An analysis of the class of gene regulatory functions implied by a biochemical model.
TL;DR: This work seeks further insights into the design of Boolean network models through the construction and analysis of a class of models that include more concrete biochemical mechanisms than the usual abstract model, including genes and gene products, dimerization, cis-binding sites, promoters and repressors.