F
Fuad G. Gwadry
Researcher at National Institutes of Health
Publications - 14
Citations - 1572
Fuad G. Gwadry is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Gene expression profiling & Regulation of gene expression. The author has an hindex of 10, co-authored 14 publications receiving 1527 citations. Previous affiliations of Fuad G. Gwadry include University of Western Ontario & Walter Reed Army Institute of Research.
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Journal ArticleDOI
Dissociated pattern of activity in visual cortices and their projections during human rapid eye movement sleep.
Allen R. Braun,Thomas J. Balkin,Thomas J. Balkin,Nancy J. Wesensten,Nancy J. Wesensten,Fuad G. Gwadry,Fuad G. Gwadry,Richard E. Carson,Richard E. Carson,M. Varga,M. Varga,Paul Baldwin,Paul Baldwin,Gregory Belenky,Gregory Belenky,Peter Herscovitch,Peter Herscovitch +16 more
TL;DR: A model for brain mechanisms subserving REM sleep where visual association cortices and their paralimbic projections may operate as a closed system dissociated from the regions at either end of the visual hierarchy that mediate interactions with the external world is suggested.
Journal Article
Diagnostic Markers That Distinguish Colon and Ovarian Adenocarcinomas Identification by Genomic, Proteomic, and Tissue Array Profiling
Satoshi Nishizuka,Sing Tsung Chen,Fuad G. Gwadry,Jes Alexander,Jes Alexander,Sylvia M. Major,Uwe Scherf,William C. Reinhold,Mark Waltham,Mark Waltham,Lu Charboneau,Lynn Young,Kimberly J. Bussey,Sohyoung Kim,Samir Lababidi,Jae K. Lee,Jae K. Lee,Stefania Pittaluga,Dominic A. Scudiero,Edward A. Sausville,Peter J. Munson,Emmanuel F. Petricoin,Lance A. Liotta,Stephen M. Hewitt,Mark Raffeld,John N. Weinstein +25 more
TL;DR: A multistep process starting with the 60 human cancer cell lines used by the National Cancer Institute to screen for new anticancer agents has the potential to produce additional markers for cancer diagnosis, prognosis, and therapy.
Journal ArticleDOI
Integrating data on DNA copy number with gene expression levels and drug sensitivities in the NCI-60 cell line panel.
Kimberly J. Bussey,Koei Chin,Samir Lababidi,Samir Lababidi,Mark Reimers,William C. Reinhold,Wen Lin Kuo,Fuad G. Gwadry,Ajay,Ajay,Hosein Kouros-Mehr,Jane Fridlyand,Ajay N. Jain,Colin Collins,Satoshi Nishizuka,Giovanni Tonon,Anna V. Roschke,Kristen Gehlhaus,Ilan R. Kirsch,Dominic A. Scudiero,Joe W. Gray,John N. Weinstein +21 more
TL;DR: The concordance of pharmacogenomic findings at the DNA and mRNA levels strongly suggests further study of l-asparaginase for possible treatment of a low-synthetase subset of clinical ovarian cancers.
Journal ArticleDOI
Gene and miRNA expression profiles in autism spectrum disorders
Mohammad Mahdi Ghahramani Seno,Pingzhao Hu,Fuad G. Gwadry,Dalila Pinto,Christian R. Marshall,Guillermo Casallo,Stephen W. Scherer,Stephen W. Scherer +7 more
TL;DR: This analysis identified several novel dysregulated genes and miRNAs in ASD compared with controls, including HEY1, SOX9, miR-486 and miR -181b, and found significant enrichment in molecules associated with neurological disorders such as Rett syndrome and those associated with nervous system development and function including long-term potentiation.
Journal ArticleDOI
Implication of SSAT by Gene Expression and Genetic Variation in Suicide and Major Depression
Adolfo Sequeira,Fuad G. Gwadry,Jarlath M. H. ffrench-Mullen,Lilian Canetti,Yves Gingras,Robert A. Casero,Guy A. Rouleau,Chawki Benkelfat,Gustavo Turecki +8 more
TL;DR: A role for SSAT, the rate-limiting enzyme in the catabolism of polyamines, in suicide and depression and a role for the SSAT342 locus in the regulation of SSAT gene expression are suggested.