S
Soichiro Morinaga
Researcher at Yokohama City University
Publications - 160
Citations - 2335
Soichiro Morinaga is an academic researcher from Yokohama City University. The author has contributed to research in topics: Pancreatic cancer & Cancer. The author has an hindex of 20, co-authored 147 publications receiving 1813 citations.
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Journal ArticleDOI
Adjuvant chemotherapy of S-1 versus gemcitabine for resected pancreatic cancer: a phase 3, open-label, randomised, non-inferiority trial (JASPAC 01)
Katsuhiko Uesaka,Narikazu Boku,Akira Fukutomi,Yukiyasu Okamura,Masaru Konishi,Ippei Matsumoto,Yuji Kaneoka,Yasuhiro Shimizu,Shoji Nakamori,Hirohiko Sakamoto,Soichiro Morinaga,Osamu Kainuma,Koji Imai,Naohiro Sata,Shoichi Hishinuma,Hitoshi Ojima,Ryuzo Yamaguchi,Satoshi Hirano,Takeshi Sudo,Yasuo Ohashi +19 more
TL;DR: This study found that adjuvant chemotherapy with S-1 can be a new standard care for resected pancreatic cancer in Japanese patients and estimated overall and relapse-free survival using the Kaplan-Meier methods and assessed non-inferiority of S-2 to gemcitabine using the Cox proportional hazard model.
Journal ArticleDOI
The clinicopathological features of colorectal mucinous adenocarcinoma and a therapeutic strategy for the disease.
Masakatsu Numata,Manabu Shiozawa,Takuo Watanabe,Hiroshi Tamagawa,Naoto Yamamoto,Soichiro Morinaga,Kazuteru Watanabe,Teni Godai,Takashi Oshima,Shoichi Fujii,Chikara Kunisaki,Yasushi Rino,Munetaka Masuda,Makoto Akaike +13 more
TL;DR: This study indentified that mucinous adenocarcinoma was associated with a worse survival compared with non-mucinous in patients with StageIII and IV disease, while survival did not differ significantly in patients diagnosed as Stage0-II disease.
Journal ArticleDOI
Randomized phase III trial of adjuvant chemotherapy with gemcitabine versus S-1 for patients with resected pancreatic cancer (JASPAC-01 study).
Katsuhiko Uesaka,Akira Fukutomi,Narikazu Boku,Hideyuki Kanemoto,Masaru Konishi,Ippei Matsumoto,Yuji Kaneoka,Yasuhiro Shimizu,Shoji Nakamori,Hirohiko Sakamoto,Soichiro Morinaga,Osamu Kainuma,Koji Imai,Naohiro Sata,Shoichi Hishinuma,Takayuki Nakamura,Michio Kanai,Satoshi Hirano,Yukinobu Yoshikawa,Yasuo Ohashi +19 more
TL;DR: It is shown that S-1 is an oral fluoropyrimidine, and shown to be non-inferior to GEM on overall survival (OS) for unresectable PC, which is a standard treatment for resected pancreatic cancer.
Journal ArticleDOI
The clinical significance of SWI/SNF complex in pancreatic cancer.
Masakatsu Numata,Soichiro Morinaga,Takuo Watanabe,Hiroshi Tamagawa,Naoto Yamamoto,Manabu Shiozawa,Yoshiyasu Nakamura,Yoichi Kameda,Shinichi Okawa,Yasushi Rino,Makoto Akaike,Munetaka Masuda,Yohei Miyagi +12 more
TL;DR: The results suggest that the specific cofactors of SWI/SNF chromatin remodeling complex certainly have roles in pancreatic cancer and high BRM, and low BAF180 are useful biomarkers for poor prognosis in Pancic cancer.
Journal Article
Overexpression of MMP-13 Gene in Colorectal Cancer with Liver Metastasis
Takanobu Yamada,Takashi Oshima,Kazue Yoshihara,Shuzo Tamura,Amane Kanazawa,Daisuke Inagaki,Naoto Yamamoto,Tsutomu Sato,Shoichi Fujii,Kazushi Numata,Chikara Kunisaki,Manabu Shiozawa,Soichiro Morinaga,Makoto Akaike,Yasushi Rino,Katsuaki Tanaka,Munetaka Masuda,Toshio Imada +17 more
TL;DR: MMP-13 gene expression is a useful predictor of liver metastasis in patients with CRC, and expression levels were higher in tumour tissue with Liver metastasis than in that without liver metastases.