Solenn Ferron

TL;DR: An open access MS/MS library with 250 metabolites, coined LDB for Lichen DataBase, providing a comprehensive coverage of lichen chemodiversity, revealing the detection of eleven unique molecules that would have been missed without LDB implementation to the GNPS.

TL;DR: In this article, a biosynthetic route to sanctis A-C was proposed by using a methyl group instead of a pendant aromatic ring at C-9, a so far unprecedented structural feature in lichen Parmotrema sancti-angelii.

TL;DR: Using a new in vitro method designed to overcome the shortage of material associated to many studies dealing with natural products, it is shown that the three major compounds isolated from the lichen Vulpicida pinastri, vulpinic acid, pinastric acid and usnic acid, were UV blocker agents.

TL;DR: New racemic dispiranic polyketides, tsavoenones A (1), B (2) and C (3), having a novel 1,7-dioxadispiro[4.0.4.4]tetradecane scaffold were isolated from the foliose lichen Parmotrema tsavoense and displayed a moderate activity against human myelogenous leukemia K562 cell line.

TL;DR: Newly reported benzylated depsidones 1: and 2: in particular inhibited α-glucosidase with IC50 values of 2.2 and 4.3 µM, respectively, and are thus more potent than the positive control, acarbose.