Sonal Deshpande

TL;DR: The enhanced biocompatibility of polymer modified, P-GQDs, is attributed to reduced reactive oxygen species generation, as measured by an intracellular ROS assay.

TL;DR: Interestingly, cubosomes loaded with Naproxen sodium, recently shown to have anticancer properties, cause more apoptosis in HeLa cells when compared to free unencapsulated drug.

TL;DR: Interestingly, it is observed that when HeLa cells were treated with doxorubicin-loaded gold core–polymeric shell NPs and exposed to rf for varying times, the mixture of the two polymeric shell nanoparticles induced more cell death as compared to the cells treated with single nanoparticles, suggesting that such multi-nanoparticle systems can be more efficacious delivery systems instead of a single multicomponent system.

TL;DR: The importance of surface architecture of cubosomes is reported by comparing their cellular uptake mechanism with poly-ε-lysine (PεL)-coated cubosome by showing that endosomal entrapment was evaded by uncoatedCubosomes, they can be preferably used for cytosolic delivery of therapeutic agents.

TL;DR: In this article, the authors demonstrate that SI-TcEP can site-specifically pattern DNA origami nanostructures with brushes containing both natural and non-natural nucleotides.