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Yonggang Ke
Researcher at Georgia Institute of Technology
Publications - 116
Citations - 8976
Yonggang Ke is an academic researcher from Georgia Institute of Technology. The author has contributed to research in topics: DNA origami & DNA nanotechnology. The author has an hindex of 36, co-authored 101 publications receiving 7200 citations. Previous affiliations of Yonggang Ke include Arizona State University & Harvard University.
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Journal ArticleDOI
Three-Dimensional Structures Self-Assembled from DNA Bricks
Yonggang Ke,Yonggang Ke,Luvena L. Ong,Luvena L. Ong,William M. Shih,William M. Shih,Peng Yin,Peng Yin +7 more
TL;DR: A simple and robust method to construct complex three-dimensional structures by using short synthetic DNA strands that are called “DNA bricks,” which can create a wide variety of nanoscale objects.
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Self-Assembled Water-Soluble Nucleic Acid Probe Tiles for Label-Free RNA Hybridization Assays
TL;DR: The DNA origami method was used to create nucleic acid probe tiles that are molecular analogs of macroscopic DNA chips that have been used to study position-dependent hybridization on the nanoscale and have also been used for label-free detection of RNA.
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Self-assembled DNA nanostructures for distance-dependent multivalent ligand-protein binding.
TL;DR: This work shows that distance-dependent multivalent binding effects can be systematically investigated by incorporating multiple-affinity ligands into DNA nanostructures with precise nanometre spatial control and illustrates the potential of using designer DNA nanoscaffolds to engineer more complex and interactive biomolecular networks.
Journal ArticleDOI
Multilayer DNA origami packed on a square lattice.
Yonggang Ke,Shawn M. Douglas,Minghui Liu,Jaswinder Sharma,Anchi Cheng,Albert Leung,Yan Liu,William M. Shih,Hao Yan +8 more
TL;DR: A more compact design for 3D origami, with layers of helices packed on a square lattice that can be folded successfully into structures of designed dimensions in a one-step annealing process, despite the increased density of DNA helices.
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DNA‐Templated Self‐Assembly of Two‐Dimensional and Periodical Gold Nanoparticle Arrays
TL;DR: When NPs are assembled onto self-assembled DNA lattices, the periodicities and interparticle spacings defined by the DNA scaffolds can be readily adjusted, with nanometer spatial precisions, which provides exquisite control in the construction of rationally defined NP architectures.