Sonia L. Gonzalez

TL;DR: The human papillomavirus E7 protein plays an important role in the viral life cycle by subverting the tight link between cellular differentiation and proliferation in normal epithelium, thus allowing the virus to replicate in differentiating epithelial cells that would have normally withdrawn from the cell division cycle.

TL;DR: It is shown that aberrant mitotic spindle pole formation caused by abnormal centrosome numbers represents an important mechanism in accounting for numeric chromosomal alterations in HPV-associated carcinogenesis.

TL;DR: Using the SAOS2 flat-cell assay as a biological indicator for pRB function, it is demonstrated that pRB degradation, not solely binding, is important for the E7-induced inactivation of pRB.

TL;DR: Results indicate that, in HASM cells, glucocorticoids alone do not alter responses to β-agonists but do inhibit IL-1β-induced β-adrenergic hyporesponsiveness, which is mediated through cyclooxygenase-2 expression and prostanoid formation.

TL;DR: Major finding in the current study is that Gal-1, -3 and -9 were detected for the first time in all the transitional breast milk samples and no differences were found when comparing the two breastfeeding time points.