S
Sonya Meeker
Researcher at Johns Hopkins University School of Medicine
Publications - 32
Citations - 2159
Sonya Meeker is an academic researcher from Johns Hopkins University School of Medicine. The author has contributed to research in topics: Nodose Ganglion & Medicine. The author has an hindex of 18, co-authored 26 publications receiving 1833 citations. Previous affiliations of Sonya Meeker include Johns Hopkins University.
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Journal ArticleDOI
Identification of a mast-cell-specific receptor crucial for pseudo-allergic drug reactions
Benjamin D. McNeil,Priyanka Pundir,Sonya Meeker,Liang Han,Bradley J. Undem,Marianna Kulka,Xinzhong Dong +6 more
TL;DR: In this paper, a mouse model was introduced to study mast cell activation by basic secretagogues and identify MRGPRX2 as a potential therapeutic target to reduce a subset of drug-induced adverse effects.
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Identification of the tracheal and laryngeal afferent neurones mediating cough in anaesthetized guinea-pigs.
Brendan J. Canning,Stuart B. Mazzone,Sonya Meeker,Nanako Mori,Sandra M. Reynolds,Bradley J. Undem +5 more
TL;DR: The data indicate that the tracheal and laryngeal afferent neurones regulating cough are polymodal Aδ‐fibres that arise from the nodose ganglia, which is quite distinct from the well‐defined rapidly and slowly adapting stretch receptors innervating the airways and lungs.
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A Role for TRPV1 in Bradykinin-Induced Excitation of Vagal Airway Afferent Nerve Terminals
TL;DR: A role for lipoxygenase products in bradykinin B2 receptor-induced activation of TRPV1 in the peripheral terminals of afferent C-fibers within guinea pig trachea is suggested.
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TRPV1 induction in airway vagal low-threshold mechanosensory neurons by allergen challenge and neurotrophic factors
TL;DR: This work addressed the hypothesis that allergic inflammation in guinea pig airways leads to a phenotypic switch in vagal tracheal cough-causing, low-threshold mechanosensitive Aδ neurons, such that they begin expressing functional transient receptor potential vanilloid (TRPV1) channels.
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Voltage-gated sodium channels in nociceptive versus non-nociceptive nodose vagal sensory neurons innervating guinea pig lungs.
Kevin Kwong,Michael J. Carr,Anna Gibbard,Tony J. Savage,Kuljit Singh,Junping Jing,Sonya Meeker,Bradley J. Undem +7 more
TL;DR: It is concluded that contrary to findings in the somatosensory neurons, TTX‐R VGSCs are not preferentially expressed in the nociceptive C‐fibre population innervating the lungs.