Marianna Kulka

TL;DR: In this paper, a mouse model was introduced to study mast cell activation by basic secretagogues and identify MRGPRX2 as a potential therapeutic target to reduce a subset of drug-induced adverse effects.

TL;DR: This review summarizes the knowledge of MC mediators and will focus on what is known about the discriminatory release of these mediators dependent upon diverse stimuli, MC phenotypes, and species of origin, as well as on the intracellular synthesis, storage, and secretory processes involved.

TL;DR: It is demonstrated that phytochemical extracts from the American cranberry (Vaccinium macrocarpon) can affect the behaviour of human prostate cancer cells in vitro and further support the potential health benefits associated with cranberries.

TL;DR: N-3 PUFA suppress FcεRI-mediated activation of mast cells, which results in reduced mediator release and a decrease in LAT and Lyn expression as well as abnormal shuttling of Fc ε receptor I to lipid rafts.