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Sophie Dupré-Crochet

Researcher at Université Paris-Saclay

Publications -  20
Citations -  613

Sophie Dupré-Crochet is an academic researcher from Université Paris-Saclay. The author has contributed to research in topics: NADPH oxidase & Phagosome. The author has an hindex of 9, co-authored 20 publications receiving 445 citations. Previous affiliations of Sophie Dupré-Crochet include Centre national de la recherche scientifique & French Institute of Health and Medical Research.

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Journal ArticleDOI

ROS production in phagocytes: why, when, and where?

Sophie Dupré-Crochet, +2 more
- 01 Oct 2013 - 
TL;DR: Examples of local ROS production, decreased degradation, signaling events, and potentially ROS‐sensitive functions are presented and the current limitations for quantitative spatiotemporal ROS detection are illustrated.
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Kinetic analysis of phagosomal production of reactive oxygen species

Asma Tlili, +7 more
- 01 Feb 2011 - 
TL;DR: It is concluded that DCFH(2)-yeast is a valuable tool to investigate the kinetics and amplitude of ROS production in individual phagosomes and is covalently attached to yeast particles and investigated their fluorescence due to oxidation in vitro and in live phagocytes.
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Stable accumulation of p67phox at the phagosomal membrane and ROS production within the phagosome

Asma Tlili, +6 more
- 01 Jan 2012 - 
TL;DR: The dynamic behavior of the crucial cytosolic NADPH oxidase component p67phox during phagocytosis is studied by videomicroscopy and suggests that once assembled in the NAD PH oxidase complex, p67 phox is stable in this complex.
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Biosensors for spatiotemporal detection of reactive oxygen species in cells and tissues

Marie Erard, +4 more
- 01 May 2018 - 
TL;DR: There is no universal method that fits all situations in physiology and cell biology and a detailed knowledge of the ROS probes is required to choose the appropriate method for a given biological problem.
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Quantitative live-cell imaging and 3D modeling reveal critical functional features in the cytosolic complex of phagocyte NADPH oxidase

Cornelia S. Ziegler, +8 more
- 15 Mar 2019 - 
TL;DR: An analytical strategy based on FRET–fluorescence lifetime imaging and fluorescence cross-correlation spectroscopy to structurally and quantitatively characterize NADPH oxidase in live cells is developed and it is revealed that the three subunits have a 1:1:1 stoichiometry and that nearly 100% of them are present in complexes in living cells.