F
Franck Fieschi
Researcher at University of Grenoble
Publications - 128
Citations - 6120
Franck Fieschi is an academic researcher from University of Grenoble. The author has contributed to research in topics: Glycomimetic & DC-SIGN. The author has an hindex of 38, co-authored 114 publications receiving 5195 citations. Previous affiliations of Franck Fieschi include French Alternative Energies and Atomic Energy Commission & Joseph Fourier University.
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Journal ArticleDOI
Dendritic‐cell‐specific ICAM3‐grabbing non‐integrin is essential for the productive infection of human dendritic cells by mosquito‐cell‐derived dengue viruses
Erika Navarro-Sanchez,Ralf Altmeyer,Ali Amara,Olivier Schwartz,Franck Fieschi,Jean-Louis Virelizier,Fernando Arenzana-Seisdedos,Philippe Desprès +7 more
TL;DR: Analysis of the interactions between DV and human‐monocyte‐derived DCs at the level of virus entry shows that the DC‐specific ICAM3‐grabbing non‐integrin (DC‐SIGN) molecule, a cell‐surface, mannose‐specific, C‐type lectin, binds mosquito‐cell‐derived DVs and allows viral replication.
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Multivalent glycoconjugates as anti-pathogenic agents
Anna Bernardi,Jesús Jiménez-Barbero,Alessandro Casnati,Christina De Castro,Tamis Darbre,Franck Fieschi,Jukka Finne,Horst Funken,Karl-Erich Jaeger,Martina Lahmann,Thisbe K. Lindhorst,Marco Marradi,Paul Messner,Antonio Molinaro,Paul V. Murphy,Cristina Nativi,Stefan Oscarson,Soledad Penadés,Francesco Peri,Roland J. Pieters,Olivier Renaudet,Jean-Reymond Reymond,Barbara Richichi,Javier Rojo,Francesco Sansone,Christina Schäffer,W. Bruce Turnbull,Trinidad Velasco-Torrijos,Sébastien Vidal,Stéphane P. Vincent,Tom Wennekes,Han Zuilhof,Han Zuilhof,Anne Imberty +33 more
TL;DR: By interfering with pathogen adhesion, such glycocompounds including glycopolymers, glycoclusters, glycodendrimers and glyconanoparticles have the potential to improve or replace antibiotic treatments that are now subverted by resistance.
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DC-SIGN and L-SIGN Are High Affinity Binding Receptors for Hepatitis C Virus Glycoprotein E2
Pierre-Yves Lozach,Hugues Lortat-Jacob,Agnès de Lacroix de Lavalette,Isabelle Staropoli,Steven K. H. Foung,Ali Amara,Corinne Houles,Franck Fieschi,Olivier Schwartz,Jean-Louis Virelizier,Fernando Arenzana-Seisdedos,Ralf Altmeyer +11 more
TL;DR: High affinity interaction of viral glycoproteins with oligomeric lectins might represent a strategy by which HCV targets to and concentrates in the liver and infects dendritic cells.
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Human Cytomegalovirus Binding to DC-SIGN Is Required for Dendritic Cell Infection and Target Cell trans-Infection
Franck Halary,Ali Amara,Hugues Lortat-Jacob,Martin Messerle,Thierry Delaunay,Corinne Houles,Franck Fieschi,Fernando Arenzana-Seisdedos,Jean Francois Moreau,Julie Déchanet-Merville +9 more
TL;DR: It is demonstrated that CMV envelope glycoprotein B is a viral ligand for DC-SIGN and DC- SIGNR and this results provide new insights into the molecular interactions contributing to cell infection by CMV and extendDC-SIGN implication in virus propagation.
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Inactivation of ribonucleotide reductase by nitric oxide.
TL;DR: Nitric oxide generated from sodium nitroprusside, S-nitrosoglutathione and the sydnonimine SIN-1 inhibits ribonucleotide reductase activity present in cytosolic extracts of TA3 mammary tumor cells.