S
Sophie Pezet
Researcher at PSL Research University
Publications - 61
Citations - 4405
Sophie Pezet is an academic researcher from PSL Research University. The author has contributed to research in topics: Neuropathic pain & Nociception. The author has an hindex of 29, co-authored 53 publications receiving 3700 citations. Previous affiliations of Sophie Pezet include King's College London & ESPCI ParisTech.
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Journal ArticleDOI
Ultrafast ultrasound localization microscopy for deep super-resolution vascular imaging
Claudia Errico,Claudia Errico,Claudia Errico,Juliette Pierre,Juliette Pierre,Juliette Pierre,Sophie Pezet,Sophie Pezet,Yann Desailly,Yann Desailly,Yann Desailly,Zsolt Lenkei,Zsolt Lenkei,Olivier Couture,Olivier Couture,Olivier Couture,Mickael Tanter,Mickael Tanter,Mickael Tanter +18 more
TL;DR: It is demonstrated in vivo that ultrasound imaging at ultrafast frame rates provides an analogue to optical localization microscopy by capturing the transient signal decorrelation of contrast agents—inert gas microbubbles that modify the microvascular blood flow in animals and humans using ultrasound.
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Neurotrophins: Mediators and Modulators of Pain
Sophie Pezet,Stephen B. McMahon +1 more
TL;DR: The chapter reviews the evidence for these roles (and briefly the effects of other neurotrophins), the range of conditions under which they act, and their mechanism of action.
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BDNF: a neuromodulator in nociceptive pathways?
TL;DR: BDNF meets many of the criteria necessary to define it as a neurotransmitter/neuromodulator in small diameter nociceptive neurons in spinal dorsal horn, suggesting that BDNF is involved in some aspects of central sensitisation in conditions of peripheral inflammation.
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Nociceptor-derived brain-derived neurotrophic factor regulates acute and inflammatory but not neuropathic pain
Jing Zhao,Anjan Seereeram,Mohammed A. Nassar,Alessandra Levato,Sophie Pezet,Gareth Hathaway,Cruz Morenilla-Palao,Caroline L. Stirling,Maria Fitzgerald,Stephen B. McMahon,Maribel Rios,John N. Wood +11 more
TL;DR: Nociceptor-derived BDNF plays an important role in regulating inflammatory pain thresholds and secondary hyperalgesia, but BDNF released only from nociceptic sensory neurons plays no role in the development of neuropathic pain.
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Brain‐derived neurotrophic factor induces NMDA receptor subunit one phosphorylation via ERK and PKC in the rat spinal cord
TL;DR: The signalling mechanisms by which BDNF exerts its neuromodulatory role on the NMDA receptor subunit 1 (NR1) suggest that BDNF modulates the activity of the receptor by phosphorylation via the kinases ERK and PKC.