S
Sören Gassel
Researcher at Goethe University Frankfurt
Publications - 8
Citations - 547
Sören Gassel is an academic researcher from Goethe University Frankfurt. The author has contributed to research in topics: Astaxanthin & Phytoene synthase. The author has an hindex of 7, co-authored 8 publications receiving 439 citations. Previous affiliations of Sören Gassel include Japan Women's University.
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Journal ArticleDOI
Biotechnological production of astaxanthin with Phaffia rhodozyma / Xanthophyllomyces dendrorhous
Isabell Schmidt,Hendrik Schewe,Sören Gassel,Chao Jin,John Buckingham,Markus Hümbelin,Gerhard Sandmann,Jens Schrader +7 more
TL;DR: This review emphasizes the potential of P. rhodozyma for the biotechnological production of astaxanthin in comparison to other natural sources such as the microalga H. pluvialis, other fungi and transgenic plants and to chemical synthesis.
Journal ArticleDOI
Aryl Polyenes, a Highly Abundant Class of Bacterial Natural Products, Are Functionally Related to Antioxidative Carotenoids.
Tim A. Schöner,Sören Gassel,Ayako Osawa,Nicholas J. Tobias,Yukari Okuno,Yui Sakakibara,Kazutoshi Shindo,Gerhard Sandmann,Helge B. Bode +8 more
TL;DR: The structure elucidation of the aryl polyene/dialkylresorcinol hybrid pigments of Variovorax paradoxus B4 is reported and it is shown for the first time that this pigment class protects the bacterium from reactive oxygen species, similarly to what is known for carotenoids.
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Genetic engineering of the complete carotenoid pathway towards enhanced astaxanthin formation in Xanthophyllomyces dendrorhous starting from a high-yield mutant
TL;DR: Classical mutagenesis with genetic engineering of the complete pathway covering improved precursor supply for carotenogenesis, enhanced metabolite flow into the pathway, and efficient conversion of intermediates into the desired end product astaxanthin is combined.
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Multiple improvement of astaxanthin biosynthesis in Xanthophyllomyces dendrorhous by a combination of conventional mutagenesis and metabolic pathway engineering
TL;DR: This combinatorial approach together with selection of an appropriate growth medium resulted in highest astaxanthin biomass contents reported to date for X. dendrorhous.
Journal ArticleDOI
The genome of the basal agaricomycete Xanthophyllomyces dendrorhous provides insights into the organization of its acetyl-CoA derived pathways and the evolution of Agaricomycotina
Rahul Sharma,Sören Gassel,Sabine Steiger,Xiaojuan Xia,Robert Bauer,Gerhard Sandmann,Marco Thines +6 more
TL;DR: The current study ascertains that Wallemia with tremelloid parenthesomes is the most basal agaricomycotinous lineage and that Cystofilobasidiales without tremelloids are deeply rooted within Tremellomycetes, suggesting that parenthesome at septal pores might be the core synapomorphy for the AgarIComycotina.