S
Soumendra Darbar
Researcher at Jadavpur University
Publications - 56
Citations - 448
Soumendra Darbar is an academic researcher from Jadavpur University. The author has contributed to research in topics: Medicine & Antioxidant. The author has an hindex of 9, co-authored 50 publications receiving 268 citations.
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Journal ArticleDOI
Citrate functionalized Mn3O4 in nanotherapy of hepatic fibrosis by oral administration
TL;DR: These findings may pave the way for practical clinical use of the C-Mn3O4 NPs as safe medication of chronic liver diseases associated with fibrosis and cirrhosis in human subjects.
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Safe and symptomatic medicinal use of surface-functionalized Mn3O4 nanoparticles for hyperbilirubinemia treatment in mice.
Nabarun Polley,Srimoyee Saha,Aniruddha Adhikari,Somtirtha Banerjee,Soumendra Darbar,Sukhen Das,Samir Kumar Pal +6 more
TL;DR: Ultrahigh efficacy of the NPs is demonstrated in symptomatic treatment of hyperbilirubinemia for rapid reduction of BR in mice compared with conventional medicine silymarin without any toxicological implications.
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Incorporation of a Biocompatible Nanozyme in Cellular Antioxidant Enzyme Cascade Reverses Huntington's Like Disorder in Preclinical Model
Aniruddha Adhikari,Susmita Mondal,Monojit Das,Monojit Das,Pritam Biswas,Uttam Pal,Soumendra Darbar,Siddhartha Sankar Bhattacharya,Debasish Pal,Tanusri Saha-Dasgupta,Anjan Kumar Das,Asim Kumar Mallick,Samir Kumar Pal,Samir Kumar Pal +13 more
TL;DR: It is shown that citrate functionalized manganese‐based biocompatible nanoscale material (C‐Mn3O4 NP) efficiently mimics glutathione peroxidase (GPx) enzyme in the physiological milieu and easily incorporates into the cellular multienzyme cascade for H2O2 scavenging.
Journal ArticleDOI
Spectroscopic Studies on Dual Role of Natural Flavonoids in Detoxification of Lead Poisoning: Bench-to-Bedside Preclinical Trial.
Aniruddha Adhikari,Soumendra Darbar,Tanima Chatterjee,Monojit Das,Nabarun Polley,Maitree Bhattacharyya,Siddhartha Sankar Bhattacharya,Debasish Pal,Samir Kumar Pal,Samir Kumar Pal +9 more
TL;DR: Heavy-metal chelation and sustainable antioxidant activity of the soluble chelate complex are found to accelerate the Pb-detoxification in the chemical bench (in vitro) and the dual action in preclinical studies is confirmed.
Journal Article
Arsenic trioxide generates oxidative stress and islet cell toxicity in rabbit
Sandip Mukherjee,D. Das,Soumendra Darbar,Maitrayee Mukherjee,Asankur Sekhar Das,Chandan Mitra +5 more
TL;DR: It appears that an alteration of the normal features of OGTT to diabetic form by an oral exposure to arsenic possibly could be a reason for islet cell damage caused by an enhanced activity of oxidative stress producing enzymes and/or by their products.