Spyros Deftereos

TL;DR: In this article, the role of inflammation in both type 1 and type 2 diabetes (T1D and T1D) pathophysiology and associated metabolic disorders, has generated increasing interest in targeting inflammation to improve prevention and control of the disease.

TL;DR: This work reviews the application of literature mining and ontology modeling and traversal to the area of drug repurposing (DR), which has emerged as a noteworthy alternative to the traditional drug development process in response to the decreased productivity of the biopharmaceutical industry.

TL;DR: Regular lifelong transfusion and chelation therapy in TM prevented premature heart disease and pulmonary hypertension, although LV dysfunction still occurred and led to heart failure.

TL;DR: This review will focus on those approaches to drug repurposing and adverse event prediction that are based on the biomedical literature that begin with an analysis of the literature and aim to reveal indirect relationships among seemingly unconnected biomedical entities.

TL;DR: Hypothyroidism is a risk factor for diabetes mellitus and subclinical hypothyroidistan-associated risk for DM is prominent only upon statin use, and identifying and treating hypothy thyroid hormone replacement therapy might reduce DM risk.