S
Stan Van Uum
Researcher at University of Western Ontario
Publications - 86
Citations - 4639
Stan Van Uum is an academic researcher from University of Western Ontario. The author has contributed to research in topics: Adrenal insufficiency & Medicine. The author has an hindex of 28, co-authored 81 publications receiving 3891 citations. Previous affiliations of Stan Van Uum include Lawson Health Research Institute & University of London.
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Journal ArticleDOI
Hair cortisol as a biological marker of chronic stress: current status, future directions and unanswered questions.
TL;DR: Because of its ability to provide a long-term, month-by-month measure of systemic cortisol exposure, hair cortisol analysis is becoming a useful tool, capable of answering clinical questions that could previously not be answered by other tests.
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Measurement of cortisol in human Hair as a biomarker of systemic exposure
TL;DR: The correlation of hair cortisol with 24-hour urine cortisol supports its relevance as biomarker for long-term exposure and determines a reference range for non-obese subjects.
Journal ArticleDOI
The Effects of Opioids and Opioid Analogs on Animal and Human Endocrine Systems
Cassidy Vuong,Stan Van Uum,Laura E. O'Dell,Kabirullah Lutfy,Kabirullah Lutfy,Theodore C. Friedman +5 more
TL;DR: Both acute and chronic effects of opioids are included, with the majority of the studies done on the acute effects although chronic effects are more physiologically relevant.
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Stress Pathways to Spontaneous Preterm Birth: The Role of Stressors, Psychological Distress, and Stress Hormones
Michael S. Kramer,John E. Lydon,Louise Séguin,Lise Goulet,Susan R. Kahn,Helen McNamara,Jacques Genest,Clément Dassa,Moy Fong Chen,Shakti Sharma,Michael J. Meaney,Steven Thomson,Stan Van Uum,Gideon Koren,Mourad Dahhou,Julie Lamoureux,Robert W. Platt +16 more
TL;DR: Neither maternal plasma CRH, hair cortisol, nor placental histopathologic features of infection/inflammation, infarction, or maternal vasculopathy were significantly associated with pregnancy-related anxiety or any other stress or distress measure, suggesting the biologic pathways underlying stress-induced preterm birth remain poorly understood.
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Heparan sulfate 6-O-sulfotransferase 1, a gene involved in extracellular sugar modifications, is mutated in patients with idiopathic hypogonadotrophic hypogonadism
Janne Tornberg,Gerasimos P. Sykiotis,Kimberly Keefe,Lacey Plummer,Xuan Hoang,Janet E. Hall,Richard Quinton,Stephanie B. Seminara,Virginia A. Hughes,Guy Van Vliet,Stan Van Uum,William F. Crowley,Hiroko Habuchi,Koji Kimata,Nelly Pitteloud,Nelly Pitteloud,Hannes E. Bülow +16 more
TL;DR: Genetic experiments in Caenorhabditis elegans reveal that HS cell-specifically regulates neural branching in vivo in concert with other IHH-associated genes, including kal-1, the F GF receptor, and FGF, consistent with a model in which KAL1 can act as a modulatory coligand with FGF to activate the FGF receptor in an HS-dependent manner.