Stefan Kircher

TL;DR: This work characterize a nuclear protein interaction cascade mediating transduction of GA signals to the activity regulation of a light-responsive transcription factor in the presence of GA, and releases PIF3 from the negative effect of DELLA proteins.

TL;DR: It is suggested that phy-induced phosphorylation of proteins such as PIF3 may represent the primary intermolecular signaling transaction of the activated photoreceptor, tagging the target protein for proteosomal degradation, possibly in nuclear speckles.

TL;DR: It is proposed that PIF3 acts transiently, and its major function is to mediate phytochrome-induced signaling during the developmental switch from skotomorphogenesis to photomorphogenesis and/or dark to light transitions.

TL;DR: Light-regulated nucleocytoplasmic partitioning of phyA and phyB is a major step in phytochrome signaling, and observations indicate that nuclear import ofphyA–GFP is controlled by a very low fluence response, whereas translocation ofPhyB–G FP is regulated by a low fluences response of phYtochrome.

TL;DR: The results suggest that the differential regulation of the translocation of phytochrome A to E into nuclei plays a role in the specification of functions, and the appearance of speckles is a functional feature of phYtochrome-regulated signaling.