R
Roland Nitschke
Researcher at University of Freiburg
Publications - 137
Citations - 10305
Roland Nitschke is an academic researcher from University of Freiburg. The author has contributed to research in topics: Cilium & Cystic fibrosis transmembrane conductance regulator. The author has an hindex of 44, co-authored 134 publications receiving 9455 citations. Previous affiliations of Roland Nitschke include National Institutes of Health & Paul Ehrlich Institute.
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Journal ArticleDOI
Quantum dots versus organic dyes as fluorescent labels
TL;DR: This work compares and evaluates the differences in physicochemical properties of common fluorescent labels, focusing on traditional organic dyes and QDs, to provide a better understanding of the advantages and limitations of both classes of chromophores.
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Constitutive Photomorphogenesis 1 and Multiple Photoreceptors Control Degradation of Phytochrome Interacting Factor 3, a Transcription Factor Required for Light Signaling in Arabidopsis
Diana Bauer,András Viczián,Stefan Kircher,Tabea Nobis,Roland Nitschke,Tim Kunkel,Kishore C. S. Panigrahi,Éva Ádám,Erzsébet Fejes,Eberhard Schäfer,Ferenc Nagy +10 more
TL;DR: It is proposed that PIF3 acts transiently, and its major function is to mediate phytochrome-induced signaling during the developmental switch from skotomorphogenesis to photomorphogenesis and/or dark to light transitions.
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TRPP2 and TRPV4 form a polymodal sensory channel complex
Michael Köttgen,Björn Buchholz,Miguel A. Garcia-Gonzalez,Fruzsina Kotsis,Xiao-Hua Fu,Mara Doerken,Christopher Boehlke,Daniel Steffl,Robert Tauber,Tomasz Wegierski,Roland Nitschke,Makoto Suzuki,Albrecht Kramer-Zucker,Gregory G. Germino,Terry Watnick,Jean Prenen,Bernd Nilius,E. Wolfgang Kuehn,Gerd Walz +18 more
TL;DR: It is found that TRPV4, like TRPP2, is an essential component of the ciliary mechanosensor, and the concept that defective ciliary flow sensing constitutes the fundamental mechanism of cystogenesis is challenged.
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Primary cilia regulate mTORC1 activity and cell size through Lkb1
Christopher Boehlke,Fruzsina Kotsis,Vishal Patel,Simone Braeg,Henriette Voelker,Saskia Bredt,Theresa Beyer,Heike Janusch,Christoph Hamann,Markus Gödel,Klaus Müller,Martin Herbst,Miriam Hornung,Mara Doerken,Michael Köttgen,Roland Nitschke,Peter Igarashi,Gerd Walz,E. Wolfgang Kuehn +18 more
TL;DR: It is shown that ablation of cilia in transgenic mice results in enlarged cells when compared with control animals, and the cilium-basal body compartment is identified as a spatially restricted activation site for Lkb1 signalling.
Journal ArticleDOI
Mechanical induction of lateral root initiation in Arabidopsis thaliana
Franck Anicet Ditengou,William Teale,Philip Kochersperger,Karl Andreas Flittner,Irina Kneuper,Eric van der Graaff,Hugues Nziengui,Francesco Pinosa,Xugang Li,Roland Nitschke,Thomas Laux,Klaus Palme +11 more
TL;DR: It is demonstrated that in Arabidopsis thaliana lateral root initiation can be induced mechanically by either gravitropic curvature or by the transient bending of a root by hand, supporting a model in which a root-tip-derived signal acts on downstream signaling molecules that specify lateral root identity.