S
Stefan Schumacher
Researcher at University of Ulm
Publications - 18
Citations - 3000
Stefan Schumacher is an academic researcher from University of Ulm. The author has contributed to research in topics: RhoG & Neurite. The author has an hindex of 13, co-authored 18 publications receiving 2797 citations. Previous affiliations of Stefan Schumacher include Charité & University of Hamburg.
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Journal ArticleDOI
CNS synaptogenesis promoted by glia-derived cholesterol
Daniela H. Mauch,Karl Nägler,Stefan Schumacher,Christian Göritz,Eva-Christina Müller,Albrecht Otto,Frank W. Pfrieger +6 more
TL;DR: Cholesterol complexed to apolipoprotein E-containing lipoproteins may explain the delayed onset of CNS synaptogenesis after glia differentiation and neurobehavioral manifestations of defects in cholesterol or lipoprotein homeostasis.
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Regulation of miRNA expression during neural cell specification.
TL;DR: Noncoding miRNA were strongly induced during neural differentiation of embryonic stem cells, suggesting the validity of the stem cell model for studying miRNA regulation in neural development.
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Post-transcriptional regulation of the let-7 microRNA during neural cell specification
F. Gregory Wulczyn,Lena Smirnova,Agnieszka Rybak,Christine Brandt,Erik Kwidzinski,Olaf Ninnemann,Michael Strehle,Andrea Seiler,Stefan Schumacher,Robert Nitsch +9 more
TL;DR: Comparison of primary, precursor, and mature let‐7 RNA levels during both embryonic brain development and neural differentiation of embryonic stem cells and embryocarcinoma (EC) cells suggest post‐transcriptional regulation ofLet‐7 accumulation.
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miR-124-regulated RhoG reduces neuronal process complexity via ELMO/Dock180/Rac1 and Cdc42 signalling.
TL;DR: RhoG emerges as a cellular conductor of Rac1 and Cdc42 activity, in turn regulated by miR‐124 to control axonal and dendritic branching.
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Comparative analysis of uncoupling protein 4 distribution in various tissues under physiological conditions and during development.
Alina Smorodchenko,Anne Rupprecht,Irina Sarilova,Irina Sarilova,Olaf Ninnemann,Anja U. Bräuer,Kristin Franke,Stefan Schumacher,Sandra Techritz,Robert Nitsch,Markus Schuelke,Elena E. Pohl +11 more
TL;DR: It is shown that UCP4 is present in fetal murine brain tissue as early as embryonic days 12-14 (E12-E14), which coincides with the beginning of neuronal differentiation.