Stefania Mejetta

TL;DR: The results indicate that metastasis-initiating cells particularly rely on dietary lipids to promote metastasis, at least in human melanoma- and breast cancer-derived tumours.

TL;DR: It is shown that Cbx4, a Polycomb Repressive Complex 1 (PRC1)-associated protein, maintains human epidermal stem cells as slow-cycling and undifferentiated, while protecting them from senescence.

TL;DR: It is shown that deletion of Jarid2 in mouse epidermis reduces the proliferation and potentiates the differentiation of postnatal epidermal progenitors, without affecting epidersmal development.

TL;DR: It is shown that cells undergoing senescence following oncogenic Ras expression have increased Z RF1 levels, and that this binds to the p15INK4b, ARF and p16INK4a promoters, and alterations in ZRF1 may contribute to tumorigenesis.