S
Stefania Viola
Researcher at Istituto Giannina Gaslini
Publications - 88
Citations - 5382
Stefania Viola is an academic researcher from Istituto Giannina Gaslini. The author has contributed to research in topics: Arthritis & Juvenile rheumatoid arthritis. The author has an hindex of 37, co-authored 88 publications receiving 4960 citations. Previous affiliations of Stefania Viola include University of Pavia & University of Genoa.
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Journal ArticleDOI
Two randomized trials of canakinumab in systemic juvenile idiopathic arthritis
Nicolino Ruperto,Hermine I. Brunner,Pierre Quartier,Tamás Constantin,Nico M Wulffraat,Gerd Horneff,Riva Brik,Liza J McCann,Ozgur Kasapcopur,Lidia Rutkowska-Sak,Rayfel Schneider,Yackov Berkun,Inmaculada Calvo,Muferet Erguven,Laurence Goffin,Michael Hofer,Tilmann Kallinich,Sheila Knupp Feitosa de Oliveira,Yosef Uziel,Stefania Viola,Kiran Nistala,Carine Wouters,Rolando Cimaz,Manuel A. Ferrandiz,Berit Flatø,M.L. Gamir,Isabelle Koné-Paut,Alexei A. Grom,Bo Magnusson,Seza Ozen,Flavio Sztajnbok,Karine Lheritier,Ken Abrams,Dennis Y. Kim,Alberto Martini,Alberto Martini,Daniel J. Lovell +36 more
TL;DR: These two phase 3 studies show the efficacy and safety of canakinumab in systemic JIA with active systemic features, and among the 100 patients who underwent randomization in the withdrawal phase, the risk of flare was lower among patients who continued to receive canakinUMab than among those who were switched to placebo.
Journal ArticleDOI
Development and validation of a composite disease activity score for juvenile idiopathic arthritis.
Alessandro Consolaro,Nicolino Ruperto,A. Bazso,Angela Pistorio,Silvia Magni-Manzoni,Giovanni Filocamo,Clara Malattia,Stefania Viola,Alberto Martini,Angelo Ravelli +9 more
TL;DR: The JADAS was found to be a valid instrument for assessment of disease activity in JIA and is potentially applicable in standard clinical care, observational studies, and clinical trials.
Journal ArticleDOI
Preliminary diagnostic guidelines for macrophage activation syndrome complicating systemic juvenile idiopathic arthritis.
Angelo Ravelli,Silvia Magni-Manzoni,Angela Pistorio,Cristina Besana,Tiziana Foti,Nicolino Ruperto,Stefania Viola,Alberto Martini +7 more
TL;DR: Diagnostic guidelines for macrophage activation syndrome complicating systemic juvenile idiopathic arthritis (S-JIA) are identified and deserve prospective validation.
Journal ArticleDOI
The pattern of response to anti-interleukin-1 treatment distinguishes two subsets of patients with systemic-onset juvenile idiopathic arthritis.
Marco Gattorno,Alessandra Piccini,Denise Lasigliè,Sara Tassi,Giacomo Brisca,Sonia Carta,Laura Delfino,Francesca Ferlito,MA Pelagatti,Francesco Caroli,Antonella Buoncompagni,Stefania Viola,Anna Loy,Marina Sironi,Annunciata Vecchi,Angelo Ravelli,Alberto Martini,Anna Rubartelli +17 more
TL;DR: Two subsets of systemic-onset JIA can be identified according to patient response to IL-1 blockade, and the 2 subsets appear to be characterized by some distinct clinical features.
Journal ArticleDOI
Patients with antinuclear antibody-positive juvenile idiopathic arthritis constitute a homogeneous subgroup irrespective of the course of joint disease.
Angelo Ravelli,Enrico Felici,Silvia Magni-Manzoni,Angela Pistorio,Cristina Novarini,Elena Bozzola,Stefania Viola,Alberto Martini +7 more
TL;DR: The results support the hypothesis that patients with similar characteristics are currently classified into different JIA categories and the value of ANA positivity as a possible modifier of the current classification system deserves consideration.