L
Liza J McCann
Researcher at University of Liverpool
Publications - 72
Citations - 2861
Liza J McCann is an academic researcher from University of Liverpool. The author has contributed to research in topics: Juvenile dermatomyositis & Medicine. The author has an hindex of 22, co-authored 62 publications receiving 2143 citations. Previous affiliations of Liza J McCann include Boston Children's Hospital & National Health Service.
Papers
More filters
Journal ArticleDOI
Two randomized trials of canakinumab in systemic juvenile idiopathic arthritis
Nicolino Ruperto,Hermine I. Brunner,Pierre Quartier,Tamás Constantin,Nico M Wulffraat,Gerd Horneff,Riva Brik,Liza J McCann,Ozgur Kasapcopur,Lidia Rutkowska-Sak,Rayfel Schneider,Yackov Berkun,Inmaculada Calvo,Muferet Erguven,Laurence Goffin,Michael Hofer,Tilmann Kallinich,Sheila Knupp Feitosa de Oliveira,Yosef Uziel,Stefania Viola,Kiran Nistala,Carine Wouters,Rolando Cimaz,Manuel A. Ferrandiz,Berit Flatø,M.L. Gamir,Isabelle Koné-Paut,Alexei A. Grom,Bo Magnusson,Seza Ozen,Flavio Sztajnbok,Karine Lheritier,Ken Abrams,Dennis Y. Kim,Alberto Martini,Alberto Martini,Daniel J. Lovell +36 more
TL;DR: These two phase 3 studies show the efficacy and safety of canakinumab in systemic JIA with active systemic features, and among the 100 patients who underwent randomization in the withdrawal phase, the risk of flare was lower among patients who continued to receive canakinUMab than among those who were switched to placebo.
Journal ArticleDOI
The Juvenile Dermatomyositis National Registry and Repository (UK and Ireland)—clinical characteristics of children recruited within the first 5 yr
Liza J McCann,A D Juggins,S M Maillard,Lucy R. Wedderburn,Joyce Davidson,K. J. Murray,Clarissa Pilkington +6 more
TL;DR: The current study reports the largest European cohort of children with dermatomyositis to date, and a fuller analysis of poor prognostic features, impact of therapy, and variable outcome of childhood myositis.
Journal ArticleDOI
Fatal Cardiac Arrhythmia and Long-QT Syndrome in a New Form of Congenital Generalized Lipodystrophy with Muscle Rippling (CGL4) Due to PTRF-CAVIN Mutations
Anna Rajab,Volker Straub,Liza J McCann,Dominik Seelow,Raymonda Varon,Rita Barresi,Anne Schulze,Barbara Lucke,Susanne Lützkendorf,Mohsen Karbasiyan,Sebastian Bachmann,Simone Spuler,Markus Schuelke +12 more
TL;DR: PTRF-CAVIN deficiency presents the phenotypic spectrum caused by a quintessential lack of functional caveolae, and is essential for Caveolae biogenesis.
Journal ArticleDOI
Disease activity, severity, and damage in the UK juvenile‐onset systemic lupus erythematosus cohort
L Watson,Valentina Leone,Clarissa Pilkington,Kjell Tullus,Satyapal Rangaraj,Janet E. McDonagh,Janet Gardner-Medwin,Nick Wilkinson,Phil Riley,Jane Tizard,Kate Armon,Manish D. Sinha,Yiannis Ioannou,Neil Archer,Kathryn Bailey,Joyce Davidson,Eileen Baildam,Gavin Cleary,Liza J McCann,Michael W. Beresford +19 more
TL;DR: The data on these patients from the UK JSLE Cohort Study indicate that severe organ involvement and significant disease activity are primary characteristics in children with juvenile SLE.
Journal ArticleDOI
The EuroMyositis registry: an international collaborative tool to facilitate myositis research
James B. Lilleker,James B. Lilleker,Jiri Vencovsky,Guochun Wang,Lucy R. Wedderburn,Louise C. Pyndt Raun Diederichsen,Jens Schmidt,Paula Oakley,Olivier Benveniste,Maria Giovanna Danieli,Katalin Dankó,Nguyen Thi Phuong Thuy,Mónica Vázquez-Del Mercado,Helena Andersson,Boel De Paepe,Jan L deBleecker,Britta Maurer,Liza J McCann,Nicolò Pipitone,Neil McHugh,Zoe E Betteridge,Zoe E Betteridge,Paul New,Robert G. Cooper,Robert G. Cooper,William E R Ollier,Janine A. Lamb,Niels Steen Krogh,Ingrid E. Lundberg,Hector Chinoy,Hector Chinoy,all EuroMyositis contributors +31 more
TL;DR: The findings emphasise that IIM is a multisystem inflammatory disease and will help inform prognosis and clinical management of patients, and demonstrate the importance of extramuscular involvement in patients with IIM, its association with smoking and its influence on disease severity.