scispace - formally typeset
A

Anna Rubartelli

Researcher at National Cancer Research Institute

Publications -  139
Citations -  17063

Anna Rubartelli is an academic researcher from National Cancer Research Institute. The author has contributed to research in topics: Secretion & Inflammation. The author has an hindex of 58, co-authored 137 publications receiving 15494 citations. Previous affiliations of Anna Rubartelli include University of Genoa & Vita-Salute San Raffaele University.

Papers
More filters
Journal ArticleDOI

Monocytic cells hyperacetylate chromatin protein HMGB1 to redirect it towards secretion

Tiziana Bonaldi, +8 more
- 15 Oct 2003 - 
TL;DR: It is shown here that in all cells HMGB1 shuttles actively between the nucleus and cytoplasm, and secreted when monocytic cells receive an appropriate second signal.
Journal ArticleDOI

The nuclear protein HMGB1 is secreted by monocytes via a non-classical, vesicle-mediated secretory pathway

Stefania Gardella, +6 more
- 01 Oct 2002 - 
TL;DR: It is shown that activation of monocytes results in the redistribution of HMGB1 from the nucleus to cytoplasmic organelles, which display ultrastructural features of endolysosomes, which means that in monocytes, non‐classical secretion can occur through vescicle compartments that are at least partially distinct.
Journal ArticleDOI

A novel secretory pathway for interleukin-1 beta, a protein lacking a signal sequence.

Anna Rubartelli, +3 more
- 01 May 1990 - 
TL;DR: It is shown that IL‐1 beta is actively secreted by activated human monocytes via a pathway of secretion different from the classical endoplasmic reticulum‐‐Golgi route, which may involve translocation of intracellular membranes and is increased by stress conditions.
Journal ArticleDOI

Differential requirement for the activation of the inflammasome for processing and release of IL-1beta in monocytes and macrophages.

Mihea G Netea, +16 more
- 05 Mar 2009 - 
TL;DR: It is demonstrated that human blood monocytes release processed IL-1beta after a one-time stimulation with either TLR2 or TLR4 ligands, resulting from constitutively activated caspase-1 and release of endogenous adenosine triphosphate.
Journal ArticleDOI

Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)

Andrea Cossarizza, +462 more
- 01 Oct 2019 - 
TL;DR: These guidelines are a consensus work of a considerable number of members of the immunology and flow cytometry community providing the theory and key practical aspects offlow cytometry enabling immunologists to avoid the common errors that often undermine immunological data.