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Stefanie Schreiber
Researcher at Otto-von-Guericke University Magdeburg
Publications - 85
Citations - 1657
Stefanie Schreiber is an academic researcher from Otto-von-Guericke University Magdeburg. The author has contributed to research in topics: Cerebral amyloid angiopathy & Amyotrophic lateral sclerosis. The author has an hindex of 20, co-authored 85 publications receiving 1200 citations. Previous affiliations of Stefanie Schreiber include Helen Wills Neuroscience Institute & German Center for Neurodegenerative Diseases.
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Blood brain barrier breakdown as the starting point of cerebral small vessel disease? - New insights from a rat model
TL;DR: It is suggested that endothelial injuries lead to multiple sites with blood brain barrier (BBB) leakage which cause an ongoing damage of the vessel wall and finally resulting in vessel ruptures and microbleeds, which represent the earliest detectable histological peculiarity of small vessel disease in SHRSP.
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The Cerebrovascular Basement Membrane: Role in the Clearance of β-amyloid and Cerebral Amyloid Angiopathy
TL;DR: This review summarizes the properties of the CVBM, its role in mediating clearance of interstitial fluids and solutes from the brain, and evidence supporting a role for CVBM in the etiology of CAA.
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Mitofusin 2 mutations affect mitochondrial function by mitochondrial DNA depletion
Stefan Vielhaber,Grazyna Debska-Vielhaber,Viktoriya Peeva,Susanne Schoeler,Alexei P. Kudin,Irina Minin,Stefanie Schreiber,Reinhard Dengler,Katja Kollewe,Werner Zuschratter,Cornelia Kornblum,Gábor Zsurka,Wolfram S. Kunz +12 more
TL;DR: The findings corroborate the hypothesis that MFN2 mutations alter mitochondrial oxidative phosphorylation by affecting mtDNA replication by deleting essential parts of mtDNA required for replication.
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Sonography of the median nerve in CMT1A, CMT2A, CMTX, and HNPP.
Stefanie Schreiber,Andreas Oldag,Cornelia Kornblum,Katja Kollewe,Siegfried Kropf,Ariel Schoenfeld,Helmut Feistner,Sibylle Jakubiczka,Wolfram S. Kunz,C. Scherlach,Claus Tempelmann,Christian Mawrin,Reinhard Dengler,Frank Schreiber,Michael Goertler,Stefan Vielhaber +15 more
TL;DR: Differences in CSA, FD, and WFR of the median nerve can be helpful in defining subtypes of hereditary neuropathies, as shown by motor and sensory nerve amplitudes in both CMT1A and CMT2A.
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The pathologic cascade of cerebrovascular lesions in SHRSP: is erythrocyte accumulation an early phase?
Stefanie Schreiber,Celine Z. Bueche,Cornelia Garz,Siegfried Kropf,Frank Angenstein,Frank Angenstein,Juergen Goldschmidt,Juergen Goldschmidt,Jens Neumann,Hans-Jochen Heinze,Hans-Jochen Heinze,Michael Goertler,Klaus G. Reymann,Holger Braun +13 more
TL;DR: Vascular pathology in SHRSP proceeds in definite stages, whereas an age-dependent accumulation of erythrocytes in capillaries and arterioles represents the homogeneous initial step of the disease.