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Wolfram S. Kunz

Researcher at University of Bonn

Publications -  288
Citations -  15255

Wolfram S. Kunz is an academic researcher from University of Bonn. The author has contributed to research in topics: Mitochondrion & Mitochondrial DNA. The author has an hindex of 61, co-authored 274 publications receiving 13514 citations. Previous affiliations of Wolfram S. Kunz include University of Ulm & Otto-von-Guericke University Magdeburg.

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Journal ArticleDOI

Analysis of shared heritability in common disorders of the brain

Verneri Anttila, +720 more
- 22 Jun 2018 - 
TL;DR: It is demonstrated that, in the general population, the personality trait neuroticism is significantly correlated with almost every psychiatric disorder and migraine, and it is shown that both psychiatric and neurological disorders have robust correlations with cognitive and personality measures.
Journal ArticleDOI

Analysis of mitochondrial function in situ in permeabilized muscle fibers, tissues and cells

Andrey V. Kuznetsov, +7 more
- 01 May 2008 - 
TL;DR: A specially designed substrate/inhibitor titration approach allows the step-by-step analysis of several mitochondrial complexes and allows the detailed characterization of functional mitochondria in their normal intracellular position and assembly, preserving essential interactions with other organelles.
Journal ArticleDOI

Characterization of Superoxide-producing Sites in Isolated Brain Mitochondria

Alexei P. Kudin, +4 more
- 06 Feb 2004 - 
TL;DR: It is proposed that reactive oxygen species can activate a self-accelerating vicious cycle causing mitochondrial damage and neuronal cell death in rat and human brain because short-term incubation of rat brain mitochondria with H2O2 induced increased H2 O2 production at this site.
Book ChapterDOI

Permeabilized cell and skinned fiber techniques in studies of mitochondrial function in vivo

Valdur Saks, +10 more
- 01 Jul 1998 - 
TL;DR: This chapter describes in details the permeabilized cell and skinned fiber techniques and their applications for studies of mitochondrial function in vivo and shows the existence of several new phenomenon — tissue dependence of the mechanism of regulation of mitochondrial respiration, and activation of respiration by selective proteolysis.
Journal ArticleDOI

Parkinson phenotype in aged PINK1-deficient mice is accompanied by progressive mitochondrial dysfunction in absence of neurodegeneration.

Suzana Gispert, +24 more
- 03 Jun 2009 - 
TL;DR: Older Pink1−/− mice show increasing mitochondrial dysfunction resulting in impaired neural activity similar to PD, in absence of overt neuronal death.