S
Stefano Iacobelli
Researcher at University of Chieti-Pescara
Publications - 207
Citations - 10027
Stefano Iacobelli is an academic researcher from University of Chieti-Pescara. The author has contributed to research in topics: Cancer & Breast cancer. The author has an hindex of 47, co-authored 200 publications receiving 9070 citations.
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Journal ArticleDOI
A comparative study of the anti-inflammatory, anticoagulant, antiangiogenic, and antiadhesive activities of nine different fucoidans from brown seaweeds
Albana Cumashi,N. A. Ushakova,M. E. Preobrazhenskaya,Armida D'Incecco,Antonio Piccoli,Licia Totani,Nicola Tinari,Galina E. Morozevich,A. E. Berman,Maria I. Bilan,Anatolii I. Usov,Nadezhda E. Ustyuzhanina,Alexey A. Grachev,Craig J. Sanderson,Maeve Kelly,Gabriel A. Rabinovich,Stefano Iacobelli,Nikolay E. Nifantiev +17 more
TL;DR: The anti-inflammatory, antiangiogenic, anticoagulant, and antiadhesive properties of fucoidans obtained from nine species of brown algae were studied to provide a new rationale for the development of potential drugs for thrombosis, inflammation, and tumor progression.
Journal ArticleDOI
Galectins and their ligands: amplifiers, silencers or tuners of the inflammatory response?
Gabriel A. Rabinovich,Linda G. Baum,Nicola Tinari,Roberto Paganelli,Clara Natoli,Fu-Tong Liu,Stefano Iacobelli +6 more
TL;DR: The current wealth of new information promises a future scenario in which individual members of the galectin family or their ligands will be used as powerful anti-inflammatory mediators and selective modulators of the immune response.
Journal Article
Biochemical and pharmacological characterization of the cyclooxygenase activity of human blood prostaglandin endoperoxide synthases.
Paola Patrignani,M. R. Panara,Anita Greco,Ornella Fusco,Clara Natoli,Stefano Iacobelli,Francesco Cipollone,A. Ganci,C Créminon,Jacques Maclouf +9 more
TL;DR: A model of human prostaglandin endoperoxide synthase-2 expression allowing the assessment of pharmacological inhibition in vitro and ex vivo was characterized and cyclooxygenase activity increased in parallel with the mass of a monocyte protein doublet analyzed by Western blot using antibodies directed against the carboxyl-terminal portion of human PGHS-2.
Journal ArticleDOI
Pertuzumab, trastuzumab, and docetaxel for HER2-positive metastatic breast cancer (CLEOPATRA): end-of-study results from a double-blind, randomised, placebo-controlled, phase 3 study
Sandra M Swain,Sandra M Swain,David Miles,Sung Bae Kim,Young-Hyuck Im,Seock-Ah Im,Vladimir Semiglazov,Eva Ciruelos,Andreas Schneeweiss,Sherene Loi,Estefania Monturus,Emma Clark,Adam Knott,Eleonora Restuccia,Mark C. Benyunes,Javier Cortes,Richy Agajanian,Rizvana Ahmad,Bahriye Aktas,Victor Hugo Alencar,Dino Amadori,Jurandyr Andrade,Fabio Franke,Catia Angiolini,Kenjiro Aogi,Jess Armor,Wichit Arpornwirat,Laura Assersohn,William Audeh,Walter E. Aulitzky,Sergio J Azevedo,Maria Alejandra Bartoli,Norberto Batista Lopez,María Bianconi,Laura Biganzoli,Ruemu E. Birhiray,Marianna Bitina,Ron Blachy,Kimberly L. Blackwell,Rita Blanchard,Paulette Blanchet,Ion Boiangiu,Barbara Bower,Christine Brezden-Masley,Adam Brufsky,Leanne Budde,Priscilla Caguioa,Lourdes Calvo,Mario Campone,Robert R. Carroll,Hugo Castro,Valorie Chan,Veena Charu,Saverio Cinieri,Michael R. Clemens,Emilio Alba Conejo,Eduardo Côrtes,Bruno Coudert,Eduardo Cronemberger,Daniel Cubero,Shaker R. Dakhil,Brooke R. Daniel,Neville Davidson,Maria De Fatima Gaui,Susana De La Cruz,Maria Del Pilar,Gilson Delgado,John Allan Ellerton,Cesar Estuardo,Louis Fehrenbacher,Jean-Marc Ferrero,Patrick J. Flynn,Malgorzata Foszczynska-Kloda,Sandra Franco,Hirofumi Fujii,Chris Gallagher,Teresa Gamucci,Nora Giacomi,Miguel Gil I Gil,Antonio Gonzalez Martin,Vera Gorbunova,Eugeny Gotovkin,Nathan B. Green,Elza Grincuka,Eva-Maria Grischke,Vincent Hansen,Jeffrey Hargis,Maik Hauschild,Roberto Hegg,Carolyn B. Hendricks,Robert Hermann,Paulo M. Hoff,Jun Horiguchi,Javier Hornedo Muguiro,Stefano Iacobelli,Kenichi Inoue,Gustavo Ismael,Yoshinori Itoh,Hiroji Iwata,Davi Jendiroba,Rosa Jochim,Alison Jones,Marianne Just,Andre Kallab,Mark Karwal,Masahiro Kashiwaba,Giraldo Kato,Peter A. Kaufman,Pirkko Kellokumpu-Lehtinen,Andreas Kirsch,Igor Kiselev,Paula Klein,Norio Kohno,Mikhail Kopp,Liljana Kostovska-Maneva,Mauricio Kotliar,Iveta Kudaba,Sherko Kümmel,Katsumasa Kuroi,Juan Lacava,Luciano Latini,Soo-Chin Lee,Mikhail Lichinitser,Christopher Lobo,Christoph Maintz,Jedzada Maneecahvakajorn,Alexander Marmé,Gloria Martinez,Norikazu Masuda,Mario Matwiejuk,Vladimir Merculov,Richard A. Michaelson,Luis Miguel,Hernandez Monroy,Filippo Montemurro,Serafin Morales,Rodrigo Moura,Volkmar Mueller,Clive Mulatero,Kazuhiko Nakagami,Takahiro Nakayama,Jeff Neidhart,An Nguyen,Reiki Nishimura,Haruki Ogata,S O'Reilly,Timothy J. O'Rourke,Douglas Otero Reye,Xuenong Ouyang,Ravi Patel,Taral Patel,Jose Luiz Pedrini,Rodrigo Pereira,Alejandra Perez,Carol Peterson,Tadeusz Pienkowski,Helio Pinczowski,Jonathan Polikoff,Wojciech Polkowski,Paola Edith Price,Sue Prill,Frank Priou,Gunta Purkalne,Seppo Pyrhoenen,Robert Quackenbush,Yoshiaki Rai,Nuria Ribelles,Jungsil Ro,Anne Robinson,Robert Robles,Gladys Rodriguez,L Roman,Shigehira Saji,Pedro Sánchez-Rovira,Nobuaki Sato,Marcus Schmidt,Claudia Schumacher,Frank Senecal,Priyanka Sharma,Zhenzhou Shen,Vadim Shirinkin,Edda Simoncini,Thitiya Sirisinha,Raymond Smith,Joohyuk Sohn,Zeljko Soldic,Tania Soria,Darcy Spicer,Vichien Srimuninnimit,Virote Sriuranpong,Elżbieta Starosławska,Petar Stefanovski,Patrapim Sunpaweravong,Julie Taguchi,Koji Takeda,Gabriel Tellez-Trevilla,Randall Thomas,Christoph Thomssen,Zetina Toache,Yutaka Tokuda,Piotr Tomczak,Celia Tosello,Koichiro Tsugawa,Dennis Tudtud,Takayuki Ueno,Brigitte Van Eyll,Mirta Varela,Nikola Vasev,Damir Vrbanec,Xiaojia Wang,Liwei Wang,Junichiro Watanabe,David Waterhouse,Birgitta Wesenberg,Duncan Wheatley,Zee Wan Wong,Sanjay Yadav,Denise A. Yardley,Tsz-Kok Yau,Winnie Yeo,Cheng Ying,Do Youn Oh +221 more
TL;DR: The end-of-study analysis of CLEOPATRA found progression-free and overall survival were significantly improved in the pertuzumab group compared with the placebo group, and the overall survival rates were also significantly improved.
Journal Article
Concentrations of galectin-3 in the sera of normal controls and cancer patients
Ida Iurisci,Nicola Tinari,Clara Natoli,Domenico Angelucci,Ettore Cianchetti,Stefano Iacobelli +5 more
TL;DR: Results suggest that circulating galectin-3 may play a role in tumor progression and the possibility of using this assay in early-stage cancer to predict metastasis should be studied.