S
Stefano M. Candura
Researcher at University of Pavia
Publications - 111
Citations - 1714
Stefano M. Candura is an academic researcher from University of Pavia. The author has contributed to research in topics: Poison control & Cholinergic. The author has an hindex of 23, co-authored 109 publications receiving 1611 citations. Previous affiliations of Stefano M. Candura include University of Washington & University of L'Aquila.
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Journal ArticleDOI
Carbon monoxide cardiotoxicity.
Cristiano Gandini,Anna F. Castoldi,Stefano M. Candura,Carlo Locatelli,Raffaella Butera,Silvia G. Priori,Luigi Manzo +6 more
TL;DR: These investigations, as well as others performed in vitro, provide support for a direct action of carbon monoxide on the heart, in addition to systemic hypoxia produced by carboxyhemoglobin formation.
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Characterization of the 5-HT receptor potentiating neuromuscular cholinergic transmission in strips of human isolated detrusor muscle.
Marcello Tonini,Eliana Messori,G. P. Franceschetti,C.A. Rizzi,Anna F. Castoldi,Teresa Coccini,Stefano M. Candura +6 more
TL;DR: The findings indicate that neuromuscular cholinergic transmission in human isolated detrusor muscle is facilitated by neural 5‐ HT receptors belonging to the 5‐HT4 subtype, and the human urinary bladder can thus be regarded as an additional site in which 5-HT4 receptors are distributed.
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Low-level exposure to methylmercury modifies muscarinic cholinergic receptor binding characteristics in rat brain and lymphocytes: physiologic implications and new opportunities in biologic monitoring.
Teresa Coccini,Giovanna Randine,Stefano M. Candura,Rossella E. Nappi,Leon D. Prockop,Luigi Manzo +5 more
TL;DR: The results suggest up-regulation of mAChRs in selected brain regions (hippocampus and cerebellum) after prolonged low-level ingestion of MeHg in rats, and cerebral effects are delayed in onset and are preceded by a marked increase in density of m aChRs on lymphocytes.
Journal Article
Biochemical markers of neurotoxicity. A review of mechanistic studies and applications.
Luigi Manzo,Francesc Artigas,Emili Martínez,Antonio Mutti,Enrico Bergamaschi,Pierluigi Nicotera,Marcello Tonini,Stefano M. Candura,David E. Ray,Lucio G. Costa +9 more
TL;DR: Current evidence suggests that certain neurochemical markers may be valuably used in animal studies as a complement to conventional laboratory tests to augment their sensitivity or predictivity, and a mechanistic research approach is required to establish which markers offer the greatest promise for application in human biomonitoring.
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Neural 5-HT4 receptors in the human isolated detrusor muscle: effects of indole, benzimidazolone and substituted benzamide agonists and antagonists.
Stefano M. Candura,Eliana Messori,G. P. Franceschetti,Gianluigi D'Agostino,Davide Vicini,Monica Tagliani,Marcello Tonini +6 more
TL;DR: In the human isolated detrusor muscle, the 5‐HT4 receptors mediating facilitation of cholinergic neuromuscular transmission are activated by indoleamines (5‐HT, 5‐MeOT), substituted benzamide (cisapride, (R,S)‐zacopride), benzoate (RS 23597) and benzimidazolone (BIMU 8) derivatives.