S
Stefano Perito
Researcher at University of Perugia
Publications - 70
Citations - 2145
Stefano Perito is an academic researcher from University of Perugia. The author has contributed to research in topics: Candida albicans & Immune system. The author has an hindex of 26, co-authored 70 publications receiving 1866 citations. Previous affiliations of Stefano Perito include Istituto Superiore di Sanità.
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Th1 and Th2 cytokines in mice with invasive aspergillosis.
Elio Cenci,Stefano Perito,Karl-Heinz Enssle,Paolo Mosci,Jean-Paul Latgé,Luigina Romani,Francesco Bistoni +6 more
TL;DR: Findings indicate that in murine invasive aspergillosis, production of IL-4 by CD4+ T cells may be one major factor discriminating susceptibility and resistance to infection.
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Secreted aspartic proteases of Candida albicans activate the NLRP3 inflammasome.
Donatella Pietrella,Neelam Pandey,Elena Gabrielli,Eva Pericolini,Stefano Perito,Lydia Kasper,Francesco Bistoni,Antonio Cassone,Bernhard Hube,Bernhard Hube,Anna Vecchiarelli +10 more
TL;DR: The data reveal novel immunoregulatory mechanisms of C. albicans and suggest that Saps contribute to the pathogenesis of candidiasis by fostering rather than evading host immunity.
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Mannoproteins from Cryptococcus neoformans promote dendritic cell maturation and activation
TL;DR: Evidence is provided that MPs foster maturation and activation of human dendritic cells (DCs) and that MP-loaded DCs are efficient stimulators of T cells and show a remarkable capacity to promote CD4 and CD8 proliferation.
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Immunomodulation by a low-virulence, agerminative variant of Candida albicans. Further evidence for macrophage activation as one of the effector mechanisms of nonspecific anti-infectious protection.
Francesco Bistoni,G. Verducci,Stefano Perito,Anna Vecchiarelli,Paolo Puccetti,P. Marconi,Antonio Cassone +6 more
TL;DR: It was possible to demonstrate that no crucial role in protection is played by cytotoxic T lymphocytes or B cells, nor by PCA-2 induced granulocytosis alone, as these effects could be reproduced in athymic mice.
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Elucidating the immunological function of the Cryptococcus neoformans capsule.
Anna Vecchiarelli,Eva Pericolini,Elena Gabrielli,Samyr Kenno,Stefano Perito,Elio Cenci,Claudia Monari +6 more
TL;DR: The encapsulated fungal pathogen Cryptococcus neoformans represents a significant agent of life-threatening infections in immunocompromised subjects and its immunological properties are reviewed.