Steinar Lundgren

TL;DR: Several metabolites of tamoxifen, including 4-hydroxylated, conjugated metabolites (Y, B, and BX), and N-desdimethyltamxifen (metabolite Z) were identified and their concentrations determined in fluids and feces from patients receiving chronic tamox ifen treatment, suggesting that the serum levels are production rate limited.

TL;DR: Choline‐containing compounds were detected in 9 of 11 carcinomas and in 2 of 11 benign lesions, demonstrating that choline compounds can be detected by in vivo 1H MRS in breast tissue under physiological conditions.

TL;DR: High‐resolution magic angle spinning MR spectroscopy of tissue biopsies provides detailed information on metabolic composition of breast cancer tissue and tumor samples could be distinguished from non‐involved samples based on relative intensities of signals from GPC, PC and choline in 1H HR MAS spectra.

TL;DR: This systematic review found that an exercise intervention program can produce short-term improvements in physical functioning and can reduce fatigue in breast cancer patients, however, more studies are needed to confirm the time-dependent observations in this study.

TL;DR: For patients with early breast cancer who met the trial selection criteria, risk adapted immediate single dose TARGIT-IORT during lumpectomy was an effective alternative to EBRT, with comparable long term efficacy for cancer control and lower non-breast cancer mortality.