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Stella Alimperti
Researcher at American Dental Association
Publications - 18
Citations - 708
Stella Alimperti is an academic researcher from American Dental Association. The author has contributed to research in topics: Cadherin & Cellular differentiation. The author has an hindex of 12, co-authored 15 publications receiving 545 citations. Previous affiliations of Stella Alimperti include Boston University & Wyss Institute for Biologically Inspired Engineering.
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Journal ArticleDOI
CDH2 and CDH11 act as regulators of stem cell fate decisions
TL;DR: It is expected that better understanding of how intercellular adhesion signaling affects lineage specification may impact biomaterial and scaffold design to control stem cell fate decisions in three-dimensional context with potential implications for tissue engineering and regenerative medicine.
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Epstein−Barr virus-encoded EBNA2 alters immune checkpoint PD-L1 expression by downregulating miR-34a in B-cell lymphomas
Eleni Anastasiadou,Dina Stroopinsky,Stella Alimperti,Alan L Jiao,Athalia Rachel Pyzer,Claudia Cippitelli,Giuseppina Pepe,Martina Severa,Jacalyn Rosenblatt,Marilena P. Etna,Simone Rieger,Bettina Kempkes,Eliana M. Coccia,Shannan J. Ho Sui,Christopher S. Chen,Stefania Uccini,David Avigan,Alberto Faggioni,Pankaj Trivedi,Frank J. Slack +19 more
TL;DR: It is found that latency III-expressing Burkitt lymphoma, diffuse large B-cell lymphomas, or their EBNA2-transfected derivatives express high PD-L1, and early B- cell factor 1 (EBF1) is identified as a repressor of miR-34a transcription.
Journal ArticleDOI
Three-dimensional biomimetic vascular model reveals a RhoA, Rac1, and N-cadherin balance in mural cell-endothelial cell-regulated barrier function
Stella Alimperti,Stella Alimperti,Teodelinda Mirabella,Teodelinda Mirabella,Varnica Bajaj,William J. Polacheck,William J. Polacheck,Dana M. Pirone,Jeremy S. Duffield,Jeroen Eyckmans,Jeroen Eyckmans,Richard K. Assoian,Christopher S. Chen,Christopher S. Chen +13 more
TL;DR: A 3D bicellular model demonstrates the continuous and rapid modulation of adhesive interactions between endothelial and mural cells and its impact on vascular barrier function and highlights an in vitro platform to study the biology of perivascular–endothelial interactions.
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Serum-free spheroid suspension culture maintains mesenchymal stem cell proliferation and differentiation potential.
TL;DR: The results suggest that serum‐free media for MSC spheroids may pave the way for scale‐up production of MSCs in clinically relevant manufacturing platforms such as stirred tank bioreactors.
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Cadherin-11 regulates both mesenchymal stem cell differentiation into smooth muscle cells and the development of contractile function in vivo.
TL;DR: This is the first report implicating cadherin-11 in SMC differentiation and contractile function in vitro as well as in vivo and indicates the presence of an autoregulatory feedback loop that committed MSCs to the SMC fate.