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Stephan Fichtlscherer
Researcher at Goethe University Frankfurt
Publications - 174
Citations - 15491
Stephan Fichtlscherer is an academic researcher from Goethe University Frankfurt. The author has contributed to research in topics: Coronary artery disease & Myocardial infarction. The author has an hindex of 28, co-authored 158 publications receiving 14601 citations. Previous affiliations of Stephan Fichtlscherer include University of Hamburg.
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Journal ArticleDOI
Number and Migratory Activity of Circulating Endothelial Progenitor Cells Inversely Correlate With Risk Factors for Coronary Artery Disease
Mariuca Vasa,Stephan Fichtlscherer,Alexandra Aicher,Klaudia Adler,Carmen Urbich,Hans Martin,Andreas M. Zeiher,Stefanie Dimmeler +7 more
TL;DR: Patients with CAD revealed reduced levels and functional impairment of EPCs, which correlated with risk factors for CAD, and hypertension was identified as a major independent predictor for impaired EPC migration.
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HMG-CoA reductase inhibitors (statins) increase endothelial progenitor cells via the PI 3-kinase/Akt pathway
Stefanie Dimmeler,Alexandra Aicher,Mariuca Vasa,Christiane Mildner-Rihm,Klaudia Adler,Michaela Tiemann,Hartmut Rütten,Stephan Fichtlscherer,Hans Martin,Andreas M. Zeiher +9 more
TL;DR: It is demonstrated that statins potently augment endothelial progenitor cell differentiation in mononuclear cells and CD34-positive hematopoietic stem cells isolated from peripheral blood.
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Circulating MicroRNAs in Patients With Coronary Artery Disease
Stephan Fichtlscherer,Salvatore De Rosa,Henrik Fox,Thomas Schwietz,Ariane Fischer,Christoph Liebetrau,Michael Weber,Christian W. Hamm,Tino Röxe,Marga Muller-Ardogan,Angelika Bonauer,Andreas M. Zeiher,Stefanie Dimmeler +12 more
TL;DR: Circulating levels of vascular and inflammation-associated microRNAs are significantly downregulated in patients with coronary artery disease.
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Reduced Number of Circulating Endothelial Progenitor Cells Predicts Future Cardiovascular Events Proof of Concept for the Clinical Importance of Endogenous Vascular Repair
Caroline Schmidt-Lucke,Lothar Rössig,Stephan Fichtlscherer,Mariuca Vasa,Martina B. Britten,Ulrike Kämper,Stefanie Dimmeler,Andreas M. Zeiher +7 more
TL;DR: Reduced levels of circulating EPCs independently predict atherosclerotic disease progression, thus supporting an important role for endogenous vascular repair to modulate the clinical course of coronary artery disease.
Journal ArticleDOI
Increase in Circulating Endothelial Progenitor Cells by Statin Therapy in Patients With Stable Coronary Artery Disease
Mariuca Vasa,Stephan Fichtlscherer,Klaudia Adler,Alexandra Aicher,Hans Martin,Andreas M. Zeiher,Stefanie Dimmeler +6 more
TL;DR: A novel mechanism of action of statin treatment in patients with stable CAD is defined: the augmentation of circulating EPCs with enhanced functional activity.