S
Stephanie G. Valderramos
Researcher at University of California, Los Angeles
Publications - 22
Citations - 3983
Stephanie G. Valderramos is an academic researcher from University of California, Los Angeles. The author has contributed to research in topics: Plasmodium falciparum & Artemisinin. The author has an hindex of 16, co-authored 22 publications receiving 3637 citations. Previous affiliations of Stephanie G. Valderramos include University of California, San Francisco & Albert Einstein College of Medicine.
Papers
More filters
Journal ArticleDOI
Zika Virus Infection in Pregnant Women in Rio de Janeiro - Preliminary Report.
Abstr Act,Patrícia Brasil,Jose Paulo Pereira,Claudia Raja Gabaglia,Luana Damasceno,Mayumi Duarte Wakimoto,Rita Maria Ribeiro Nogueira,Patricia Carvalho de Sequeira,André M. Siqueira,Liege Maria Abreu de Carvalho,Denise Cotrim da Cunha,Guilherme Amaral Calvet,Elizabeth de Souza Neves,Maria Elisabeth Lopes Moreira,Ana Elisa Rodrigues Baião,Paulo Roberto Nassar de Carvalho,Carla Janzen,Stephanie G. Valderramos,James D. Cherry,Ana Maria Bispo de Filippis,Karin Nielsen-Saines +20 more
TL;DR: Despite mild clinical symptoms in the mother, ZIKV infection during pregnancy is deleterious to the fetus and is associated with fetal death, fetal growth restriction, and a spectrum of central nervous system abnormalities.
Journal ArticleDOI
Zika Virus Infection in Pregnant Women in Rio de Janeiro—Preliminary Report
Patrícia Brasil,Jose Paulo Pereira,Claudia Raja Gabaglia,Luana Damasceno,Mayumi Duarte Wakimoto,Rita Maria Ribeiro Nogueira,Patricia Carvalho de Sequeira,André M. Siqueira,Liege Maria Abreu de Carvalho,Denise Cotrim da Cunha,Guilherme Amaral Calvet,Elizabeth de Souza Neves,Maria Elisabeth Lopes Moreira,Ana Elisa Rodrigues Baião,Paulo Roberto Nassar de Carvalho,Carla Janzen,Stephanie G. Valderramos,James D. Cherry,Ana Maria Bispo de Filippis,Karin Nielsen-Saines +19 more
TL;DR: ZIKV was first identified in Brazil in 2015 by reverse transcriptase–polymerase chain reaction assays of serum specimens from patients who presented with a dengue-like illness that was characterized by rash, fever, myalgias, arthralgias, and conjunctivitis.
Journal ArticleDOI
Decreasing pfmdr1 copy number in plasmodium falciparum malaria heightens susceptibility to mefloquine, lumefantrine, halofantrine, quinine, and artemisinin.
Amar Bir Singh Sidhu,Anne-Catrin Uhlemann,Stephanie G. Valderramos,Juan Carlos Valderramos,Sanjeev Krishna,David A. Fidock +5 more
TL;DR: The importance of pfmdr1 copy number in determining P. falciparum susceptibility to multiple agents currently being used to combat malaria caused by multidrug-resistant parasites is highlighted.
Journal ArticleDOI
pfmdr1 mutations contribute to quinine resistance and enhance mefloquine and artemisinin sensitivity in Plasmodium falciparum.
TL;DR: The hypothesis that pfmdr1 3′ point mutations can significantly affect parasite susceptibility to a wide range of antimalarial drug susceptibility in a strain‐specific manner that depends on the parasite genetic background is supported.
Journal ArticleDOI
From Mosquitos to Humans: Genetic Evolution of Zika Virus
Lulan Wang,Lulan Wang,Stephanie G. Valderramos,Aiping Wu,Songying Ouyang,Songying Ouyang,Chunfeng Li,Patrícia Brasil,Myrna C. Bonaldo,Thomas J. Coates,Karin Nielsen-Saines,Taijiao Jiang,Roghiyh Aliyari,Genhong Cheng,Genhong Cheng +14 more
TL;DR: Sequence analysis of all 41 known ZIKV RNA open reading frames to date indicates that ZikV has undergone significant changes in both protein and nucleotide sequences during the past half century.