Stephanie Pedersen

TL;DR: This is currently the largest post-PARPi study identifying genomic mechanisms of resistance to PARPis and the activity of cediranib–olaparib varied according to the PARPi resistance mechanism.

TL;DR: In this article , the authors demonstrate integrated, longitudinal cfDNA sequencing using multi-omic approaches is more effective than unimodal analysis and support the use of frequent blood testing using comprehensive genomic, fragmentomic, and epigenomic techniques.

TL;DR: In this paper , an exploratory biomarker analysis of refractory tumors collected from pediatric patients before atezolizumab therapy (iMATRIX-atezolizumaab, NCT02541604 ).

TL;DR: Soleimani et al. as mentioned in this paper used a Graph Neural Network (GNN) model to track the specificity-associated features of local and systemic TCR repertoires in response to ICB.

TL;DR: In this article , the Cancer Genome Atlas (TCGA) has identified four molecular subgroups of endometrial cancers (EC) with distinct differences in prognosis and response to adjuvant treatment.