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Stephen D. Turner
Researcher at University of Virginia
Publications - 75
Citations - 5363
Stephen D. Turner is an academic researcher from University of Virginia. The author has contributed to research in topics: Biology & Computer science. The author has an hindex of 29, co-authored 62 publications receiving 4168 citations. Previous affiliations of Stephen D. Turner include Vanderbilt University & University of Hawaii.
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Journal ArticleDOI
qqman: an R package for visualizing GWAS results using Q-Q and manhattan plots
TL;DR: The qqman package enables the flexible creation of manhattan plots, both genome-wide and for single chromosomes, with optional highlighting of SNPs of interest.
Posted ContentDOI
qqman: an R package for visualizing GWAS results using Q-Q and manhattan plots
TL;DR: The qqman package enables the flexible creation of manhattan plots, both genome-wide and for single chromosomes, with optional highlighting of SNPs of interest.
Journal ArticleDOI
Unexpected role of interferon-γ in regulating neuronal connectivity and social behaviour
Anthony J. Filiano,Yang Xu,Nicholas J. Tustison,Rachel Marsh,Wendy Baker,Igor Smirnov,Christopher C. Overall,Sachin P. Gadani,Stephen D. Turner,Zhiping Weng,Sayeda Najamussahar Peerzade,Hao Chen,Kevin S. Lee,Michael Scott,Mark P. Beenhakker,Vladimir Litvak,Jonathan Kipnis +16 more
TL;DR: It is shown that meningeal immunity is also critical for social behaviour; mice deficient in adaptive immunity exhibit social deficits and hyper-connectivity of fronto-cortical brain regions, and suggests a co-evolutionary link between social behaviour and an anti-pathogen immune response driven by IFN-γ signalling.
Journal ArticleDOI
Quality control procedures for genome-wide association studies.
Stephen D. Turner,Loren L. Armstrong,Yuki Bradford,Christopher S. Carlson,Dana C. Crawford,Andrew Crenshaw,Mariza de Andrade,Kimberly F. Doheny,Jonathan L. Haines,Geoffrey Hayes,Gail P. Jarvik,Lan Jiang,Iftikhar J. Kullo,Rongling Li,Hua Ling,Teri A. Manolio,Martha E. Matsumoto,Catherine A. McCarty,Andrew McDavid,Daniel B. Mirel,Justin Paschall,Elizabeth W. Pugh,Luke V. Rasmussen,Russell A. Wilke,Rebecca L. Zuvich,Marylyn D. Ritchie +25 more
TL;DR: Common issues associated with QC of GWAS data are discussed, including data file formats, software packages for data manipulation and analysis, sex chromosome anomalies, sample identity, sample relatedness, population substructure, batch effects, and marker quality.
Journal ArticleDOI
Whole-Genome Sequencing in Outbreak Analysis
TL;DR: The current application of next-generation sequencing (NGS) technology to microbial WGS and microbial forensics is reviewed and will enable an improved public health response whether a disease outbreak was initiated by natural events or by accidental or deliberate human activity.