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Stephen Gwilym
Researcher at University of Oxford
Publications - 77
Citations - 2642
Stephen Gwilym is an academic researcher from University of Oxford. The author has contributed to research in topics: Medicine & Osteoarthritis. The author has an hindex of 19, co-authored 65 publications receiving 2111 citations. Previous affiliations of Stephen Gwilym include John Radcliffe Hospital & Nuffield Orthopaedic Centre.
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Journal ArticleDOI
Psychophysical and functional imaging evidence supporting the presence of central sensitization in a cohort of osteoarthritis patients.
Stephen Gwilym,John R. Keltner,Catherine E. Warnaby,Andrew Carr,Boris A. Chizh,Iain P. Chessell,Irene Tracey +6 more
TL;DR: Increased activity with the periaqueductal grey matter associated with stimulation of the skin in referred pain areas of patients with hip OA offers a central target for analgesia aimed at improving the treatment of this largely peripheral disease.
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Arthroscopic subacromial decompression for subacromial shoulder pain (CSAW): a multicentre, pragmatic, parallel group, placebo-controlled, three-group, randomised surgical trial
David J Beard,Jonathan Rees,Jonathan Cook,Ines Rombach,Cushla D Cooper,Naomi Merritt,Beverly A. Shirkey,Jenny L Donovan,Stephen Gwilym,Julian Savulescu,Jane Moser,Alastair Gray,Marcus Jepson,Irene Tracey,Andrew Judge,Karolina Wartolowska,Andrew Carr +16 more
TL;DR: The findings question the value of this operation for subacromial shoulder pain and function, and this should be communicated to patients during the shared treatment decision-making process.
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Thalamic Atrophy Associated With Painful Osteoarthritis of the Hip Is Reversible After Arthroplasty A Longitudinal Voxel-Based Morphometric Study
TL;DR: The findings confirm that gray matter volume decreases within the left thalamus in the presence of chronic pain and disability in patients with hip OA and show that these thalamic volume changes reverse after hip arthroplasty and are associated with decreased pain and increased function.
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Evidence that central sensitisation is present in patients with shoulder impingement syndrome and influences the outcome after surgery
TL;DR: If patients with shoulder pain associated with impingement had relatively high levels of central sensitisation pre-operatively, as indicated by higher levels of punctate hyperalgesia and/or referred pain, the outcome three months after subacromial decompression was significantly worse.
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Chronic inflammation is a feature of Achilles tendinopathy and rupture.
Stephanie G. Dakin,J L Newton,Fernando O. Martinez,Robert Hedley,Stephen Gwilym,Natasha Jones,Hamish Reid,Simon Wood,Graham Wells,Louise Appleton,Kim Wheway,Bridget Watkins,Andrew Carr +12 more
TL;DR: Tissue and cells derived from tendinopathic and ruptured Achilles tendons show evidence of chronic (non-resolving) inflammation and strategies that target chronic inflammation are of potential therapeutic benefit for patients with Achilles tendon disease.